Benzonatate
- Atc Codes:R05DB01
- CAS Codes:104-31-4
- PHARMGKB ID:104-31-4
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Inhibits
- Drug Interactions
- Dosage
- Special Considerations
Brand Names
North America
Canada: Tessalon; USA: Tessalon.
Latin America
Mexico: Beknol, Benzonal, Benzonatato, Capsicof, D-Tato, Lemtosid, Nafatosín, Novapsyl, Pebegal, Pharben, Supracof, Tesalón, Tesopén, Texovén, Tuzzil.
Drug combinations
Chemistry
Benzonatate: C~30~H~53~NO~11~. Mw: approx. 603.00. (1) Benzoic acid, 4-(butylamino)-, 2,5,8,11,14,17,20,23,26-nonaoxaoctacos-28-yl ester; (2) 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-yl p-(butylamino)benzoate. CAS-104-31-4.
Pharmacologic Category
Antitussives. (ATC-Code: R05DB01).
Mechanism of action
Suppresses cough by topical anesthetic action on the respiratory stretch receptors.
Therapeutic use
Symptomatic relief of nonproductive cough.
Pregnancy and lactiation implications
Use with caution during pregnancy or lactation.
Unlabeled use
Contraindications
Hypersensitivity to benzonatate, related compounds (such as tetracaine), or any component of the formulation.
Warnings and precautions
Release of benzonatate in the mouth can cause a temporary local anesthesia of the oral mucosa and difficulty swallowing. May produce changes in CNS, such as drowsiness, impaired coordination, blurred vision, increased anxiety, dizziness, sedation, tremor, agitation. May produce upset stomach or nausea. May produce numbness in chest or feeling of chill.