Magnesium Gluconate
- Atc Codes:A12CC03
- CAS Codes:59625-89-7#3632-91-5
- PHARMGKB ID:59625-89-7#3632-91-5
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Belgium: Ultra-Mg; Germany: Magnerot; Luxembourg: Ultra Mg; Poland: Provitina Magnesium.
North America
USA: Mag G, Magonate, Magtrate.
Drug combinations
Chemistry
Magnesium Gluconate: C~12~H~22~MgO~14~ xH~2~O. Mw: 414.60 (anhydrous). (1) D-Gluconic acid, magnesium salt (2:1), hydrate; (2) Magnesium D-gluconate (1:2) hydrate. CAS-59625-89-7 (dihydrate); CAS-3632-91-5 (anhydrous).
Pharmacologic Category
Replacement Preparations; Electrolyte Solutions. Oral Electrolyte Supplement. Nutritional Supplements. Magnesium Salt. (ATC-Code: A12CC03).
Mechanism of action
Cofactor in many enzymatic reactions in the body involving protein synthesis and carbohydrate metabolism. Actions on lipoprotein lipase found to be important in reducing serum cholesterol and on sodium/potassium ATPase in promoting polarization (e.g. neuromuscular functioning).
Therapeutic use
Dietary supplement.
Pregnancy and lactiation implications
Magnesium crosses placenta. Magnesium found in breast milk.
Unlabeled use
Contraindications
Hypersensitivity to any component of the formulation.
Warnings and precautions
For occasional use only (serious side-effects may occur with prolonged use). Use with extreme caution in myasthenia gravis or other neuromuscular disease. Use with caution in renal impairment (accumulation might lead to magnesium intoxication).