Dexpanthenol
- Atc Codes:A11HA30#D03AX03#S01XA12
- CAS Codes:81-13-0
- PHARMGKB ID:81-13-0
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Nutrition/Nutraceutical Interactions
- Dosage
Brand Names
Europe
Austria: Bepanthen, Corneregel, Dexpanthenol; Bulgaria: Dexanol, Panthenol, Pantogel; Czech Republic: Bepanthen, Panthenol; Estonia: Bepanthen; Finland: Bepanthen, Dexpanthenol; France: Bepanthene; Germany: Bepanthen, Dexpa, Dexpanthenol, Marolderm, Otriven Pflege mit Dexpanthenol, Panthenol, Siozwo SANA; Greece: Bepanthene, Corneregel; Hungary: Corneregel, Panthenol; Italy: Bepanten; Latvia: Bepanthen, Corneregel, Dexpanthenol, Panthenol; Lithuania: Bepanthen, Corneregel, Panthenol; Luxembourg: Bepanthen, Corneregel; Poland: Bepanthen, Corneregel, Dermopanten, Otrivin Saline, Panthenol; Portugal: Bepanthene, Pantenol Labesfal; Romania: Bepanthen, Corneregel, Panthenol; Slovakia: Corneregel, Panthenol; Slovenia: Panthenol; Spain: Bepanthene; Sweden: Bepanthen.
Latin America
Brazil: Bepantol, Uvless; Mexico: Bepanthen, Corneregel.
Asia
Japan: Panthenyl, Pantol.
Drug combinations
Dexpanthenol: Adenosine; Allantoin; Aloe Vera; Ascorbic Acid (Vitamin C); Benzocaine; Beeswax; Biotin (Vitamin B~7~); Bisabolol Alpha; Boric Acid; Cade Oil; Chamomile Flowers; Chlorhexidine; Cholecalciferol (Vitamin D~3~); Cinchona officinalis; Cobalt; Cooper; Cyanocobalmin (Vitamin B~12~); Dimethyl Sulfoxide; Ergocalciferol (Vitamin D~2~); Folic Acid (Vitamin B~9~); Heparin; Hyaluronic Acid; Horse Chestnut Seeds; Iron; Ketoconazole; Lactic Acid; Lanolin Oil; Magnesium; Manganese; Mint Oil; Molybdenum; Niacinamide (Vitamin B~3~); Panax ginseng; Pantothenic Acid (Vitamin B~5~); Pilocarpine; Potassium; Pyridoxine (Vitamin B~6~); Resorcinol; Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Salicylic Acid; Shea Butter; Thiamin (Vitamin B~1~); Tocophenol (Vitamin E); Tretinoin; Triclosan; Urea; Urtica dioica; Vaseline; Xylometazoline; Zinc
Chemistry
Dexpanthenol: C~9~H~19~NO~4~. Mw: 205.25. (1) Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)-; (2) D-(+)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide. CAS-81-13-0 (1970).
Pharmacologic Category
Vitamins; Vitamin B Complex. Gastrointestinal Stimulant Agent. Topical Skin Product. Homeopathic product. (ATC-Code: A11HA30; D03AX03; S01XA12).
Mechanism of action
Dexpanthenol is the alcohol of pantothenic acid (vitamin B~5~) which is converted internally to coenzyme A.
Therapeutic use
Prophylactic use to minimize paralytic ileus. Treatment of postoperative distention. Topical to relieve itching and to aid healing of minor dermatoses.
Pregnancy and lactiation implications
Use only if possible benefit outweighs potential risk to the fetus. Caution during lactation.
Unlabeled use
Contraindications
Hypersensitivity to dexpanthenol or any component of the formulation. Mechanical obstruction of ileus.
Warnings and precautions
Treatment of paralytic ileus should include correction of fluid and electrolyte imbalance, anemia, hypoproteinemia, infection and the avoidance of drugs which decrease motility.