Magnesium Glucoheptonate
- Atc Codes:A12CC
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
North America
Canada: Magnelium, Magnolex, Magnorol.
Drug combinations
Chemistry
Magnesium alpha-Glucoheptonate: C~14~H~26~MgO~16~. Mw: 474.65. Magnesium 2,3,4,5,6,7-hexahydroxyheptanoate.
Pharmacologic Category
Replacement Preparations; Electrolyte Solutions. Nutritional Supplements. Magnesium Salt. (ATC-Code: A12CC).
Mechanism of action
When taken orally, magnesium promotes bowel evacuation by causing osmotic retention of fluid which distends colon with increased peristaltic activity. Parenterally, magnesium decreases acetylcholine in motor nerve terminals and acts on myocardium by slowing rate of S-A node impulse formation and prolonging conduction time.
Therapeutic use
Treatment and prevention of hypomagnesemia.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Heart block. Serious renal impairment. Myocardial damage. Hepatitis. Addison’s disease.
Warnings and precautions
For occasional use only (serious side-effects might occur with prolonged use). Use with extreme caution in myasthenia gravis or other neuromuscular disease. Use with caution in renal impairment (accumulation might lead to magnesium intoxication).