Betahistine
- Atc Codes:N07CA01
- CAS Codes:5579-84-0#5638-76-6
- PHARMGKB ID:5579-84-0#5638-76-6
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: Betaserc; Belgium: Bétahistine, Betaserc, Docbetahi; Bulgaria: Betaserc; Czech Republic: Avertin, Betahistin, Betaserc, Menivert, Microser, Polvertic, Serprin, Vertisan, Zenostig; Denmark: Betaserc; Estonia: Betahistin, Betaserc; Finland: Betahistin, Betaserc; France: Betahistine, Betaserc, Extovyl, Lectil, Serc; Greece: Antivom, Betaserc, Katabexin, Ribrain, Riva; Hungary: Acuver, Betagen, Betahistin, Betarevin, Betaserc, Elven, Imoxon, Microser, Polvertic, Zenostig; Ireland: Betahecon, By-Vertin, Serc, Vertigon; Italy: Microser, Vertiserc; Luxembourg: Betahistine, Betaserc, Lobione; Netherlands: Betahistine, Betakele, Betakile, Betakole, Betakule, Betalase, Betalese, Betalise, Betalose, Betaluse, Betarave, Betarive, Betarove, Betaruve, Betaserc, Divetrin, Marbeta; Poland: Betaserc, Hisitimerck, Microser; Portugal: Beta-histina, Betaserc; Romania: Acuver, Betaserc, Microser, Urutal, Vertisan, Vestibo; Slovakia: Avertin, Betahistine, Betaserc, Emperin, Microser, Polvertic, Urutal, Vertisan, Zenostig; Spain: Fidium, Serc; UK: Betahistine, Serc.
North America
Canada: Serc.
Latin America
Argentina: Betaserc, Meniex, Microser, Ronistina, Travelmín; Mexico: Serc.
Asia
Japan: Bymeniere, Convermin M, Deanosart, Histatine, Meniace, Menietol, Menitazine, Merislon, Metahislon, Metroneana, Mitapop, Papaverian, Remark, Suzutolon.
Drug combinations
Chemistry
Betahistine Hydrochloride: C~8~H~12~N~2~ 2HCl. Mw: 209.12. (1) 2-Pyridineethanamine, N-methyl-, dihydrochloride; (2) 2-[2-(Methylamino)ethyl]pyridine dihydrochloride. CAS-5579-84-0; CAS-5638-76-6 (betahistine)(1962).
Pharmacologic Category
Central Nervous System Agents, Miscellaneous; Histamine H~1~ Agonist. (ATC-Code: N07CA01).
Mechanism of action
Therapeutic use
Ménière’s disease (to decrease episodes of vertigo).
Pregnancy and lactiation implications
There are no adequate studies in pregnant women. Use only when potential benefit to the woman outweighs possible risk to fetus. Use with caution during lactation.
Unlabeled use
Contraindications
Hypersensitivity to betahistine or any component of the formulation. Peptic ulcer disease. Pheochromocytoma.
Warnings and precautions
Use with caution in cardiovascular or respiratory diseases. Avoid concurrent use with antihistamines. Not recommended for use in children.