Bepotastine
- Atc Codes:S01GX
- CAS Codes:190786-44-8
- PHARMGKB ID:190786-44-8
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
North America
USA: Bepreve.
Asia
Japan: Talion.
Drug combinations
Chemistry
Bepotastine Besilate: C~27~H~31~ClN~2~O~6~S. Mw: 547.06. (1) Benzenesulfonic acid; 4-[4-[(S)-(4-chlorophenyl)-pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid; (2)(+)-4-[[(S)-p-chloro-α-2-pyridylbenzyl]oxy]-1-piperidine butyric acid monobenzenesulfonate. CAS-190786-44-8.
Pharmacologic Category
EENT Preparations; Antiallergic Agents; Histamine H~1~ Antagonist. (ATC-Code: S01GX).
Mechanism of action
Direct H~1~-receptor antagonist; inhibits release of histamine from mast cells.
Therapeutic use
Treatment of itching associated with allergic conjunctivitis.
Pregnancy and lactiation implications
Not recommended during pregnancy and lactation.
Unlabeled use
Contraindications
None known to date.
Warnings and precautions
Should not be used to treat contact lens-related irritation. Remove contact lenses prior to instillation.