Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Nutrition/Nutraceutical Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Austria: Campral; Belgium: Campral; Czech Republic: Campral; Denmark: Campral; France: Aotal; Germany: Campral; Hungary: Campral; Ireland: Campral; Netherlands: Campral; Poland: Campral; Portugal: Campral; Spain: Campral, Zulex; Sweden: Aotal, Campral; UK: Campral.

North America

Canada: Campral; USA: Campral.

Latin America

Mexico: Campral.

Drug combinations


Acamprosate Calcium: C~10~H~20~CaN~2~O~8~S~2~. Mw: 400.48. (1) 1-Propanesulfonic acid, 3-(acetylamino)-, calcium salt (2:1); (2) Calcium 3-(acetylamino)propane-1-sulfonate. CAS-77337-73-6; CAS-77337-76-9 (acamprosate)(2002).

Pharmacologic Category

Central Nervous System Agents, Miscellaneous; GABA Agonist/Glutamate Antagonists. (ATC-Code: N07BB03).

Mechanism of action

Increases GABA-ergic system activity and decreases glutamate activity, including a decrease in activity at N-methyl D-aspartate (NMDA) receptors. Restores balance to disrupted GABA and glutamate activities in alcohol dependence. Reduces alcohol intake.

Therapeutic use

Maintenance of alcohol abstinence.

Pregnancy and lactiation implications

Use only if potential benefit outweighs possible risk to the fetus. Caution during lactation.

Unlabeled use


Hypersensitivity to acamprosate or any component of the formulation. Severe renal impairment (CrCl <30 mL/minute).

Warnings and precautions

Caution in depression and suicidal ideation. Does not eliminate/diminish symptoms of alcohol withdrawal. Caution in moderate renal impairment (CrCl 30-50 mL/minute). Contraindicated in severe renal impairment. May contain sulfites.



Legal Notice
Privacy Policy
Cookie Policy


Phone: +34-981-780505
Location: Sta Marta de, C. P. Babío, S/N, 15165 Bergondo, A Coruña

Copyright © 2023 WAGEM

Add to cart