Table of contents

  • Brand Names
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Unlabeled Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Caution and personalized dose adjustment in patients with the following genotypes
  • Other genes that may be involved
  • Inhibits
  • Drug Interactions
  • Dosage
  • Special Considerations

Brand Names


Austria: Albuminativ, Albunorm, Flexbumin, Human Albumin, Humanalbumin, Plasma Protein; Bulgaria: Albiomin, Albumin, Albunorm, Human Albumin, Plasbumin; Cyprus: Albumin Human, Human Albumin, Zenalb; Czech Republic: Albumin Human, Albunorm, Flexbumin, Human Albumin; Denmark: Albuminativ, Human Albumin, Octalbin; Estonia: Albumin, Albunorm, Flexbumin; Finland: Albuman, Albumin, Albuminativ, Alk-Diluent, Octalbin, Pulmocis; France: Albumine Humaine, Octalbine, Pulmocis, Vialebex; Germany: Albumin Human; Greece: Albiomin, Albuminativ, Albumine, Alburex, Flexbumin, Human Albumin, Nialbumin, Plasbumin, Zenalb; Hungary: Human Albumin, Flexbumin; Ireland: Albumin Human, Albuminativ, Albunorm, Flexbumin, Human Albumin, Pulmocis; Italy: Albiomin, Albital, Albumina, Alburex, Albutein, Octalbin, Plasbumin, Uman Albumin; Latvia: Albumin, Albunorm, Flexbumin, Human Albumin; Lithuania: Albumin, Albunorm, Flexbumin, Nanocoll; Luxembourg: Albumine Humaine, Albutein, Octalbin, Vialebex; Malta: Cealb, Flexbumin, Human Albumin, Uman Albumin, Zenalb; Netherlands: Albuman, Albumine, Cealb, Flexbumin, Humaan Albumine, Octalbine; Poland: Albiomin, Albunorm, Flexbumin, Human Albumin, Uman Albumin; Portugal: Albiomin, Albumina Humana, Albuminativ, Albumine, Albunorm, Alburex, Flexbumin; Romania: Albiomin, Albumina Umana, Albunorm, Human Albumin, Uman Albumin, Vialebex; Slovakia: Albumin Human, Albunorm, Flexbumin, Human Albumin; Slovenia: Flexbumin, Humani Albumin; Spain: Albumina Humana, Octalbin; Sweden: Albumin, Albuminativ, Albunorm, Flexbumin, Pulmocis; UK: Zenalb.

North America

Canada: Albumin, Alburex, Albutein, Buminate, Plasbumin.

Latin America

Argentina: Albumina Humana, Buminate, Flexbumin; Brazil: Albumina Humana, Albuminar, Beribumin, Plasbumin; Mexico: Albumina Humana, Albunate, Octalbin, Seroalbumina Humana, Vanderbumin.


Japan: Albuminar, Albumin.

Drug combinations


Pharmacologic Category

Blood Derivatives; Colloid plasma volume expander. (ATC-Code: B05AA01).

Mechanism of action

Provides an increase in intravascular oncotic pressure and causes mobilization of fluids from interstitial into intravascular space.

Therapeutic use

Plasma volume expansion and maintenance of cardiac output in the treatment of certain types of shock or impending shock. May be useful for burn patients, ARDS, and cardiopulmonary bypass. Other uses considered by some investigators (but not proven) are retroperitoneal surgery, peritonitis, and ascites. Unless the condition responsible for hypoproteinemia can be corrected, albumin can provide only symptomatic relief or supportive treatment.

Pregnancy and lactiation implications

Use with caution in pregnancy. Compatible with lactation.

Unlabeled use

In cirrhotics, administered with diuretics to help facilitate diuresis. Large volume paracentesis. Volume expansion in dehydrated, mildly-hypotensive cirrhotics.


Hypersensitivity to albumin or any component of the formulation. Patients with severe anemia or cardiac failure.

Warnings and precautions

All patients should be observed for signs of hypervolemia such as pulmonary edema. Use with caution in hepatic impairment; protein load may exacerbate or precipitate encephalopathy. Use with caution in renal impairment; protein load may precipitate azotemia. Avoid 25% concentration in preterm infants due to risk of intraventricular hemorrhage. Use with caution in those patients for whom sodium restriction is necessary. Nutritional supplementation is not an appropriate indication for albumin.



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