Alcohol (Ethyl)
- Atc Codes:D08AX08#V03AB16#V03AZ01
- CAS Codes:64-17-5
- PHARMGKB ID:64-17-5
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Unlabeled Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Caution and personalized dose adjustment in patients with the following genotypes
- Other genes that may be involved
- Substrate of
- Inhibits
- Induces
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Bulgaria: Spiritus Aethylicus; France: Alcool Modifie; Spain: Alcohol.
Drug combinations
Chemistry
Alcohol (Ethyl): C~2~H~6~O. Mw: 46.07. (1) Ethanol. CAS-64-17-5.
Pharmacologic Category
Local Anti-Infectives, Miscellaneous (Topical). Antidotes. (ATC-Codes: D08AX08; V03AB16; V03AZ01).
Mechanism of action
Used to treat ethylene glycol or methanol toxicity, competitively inhibits their metabolism and decreases the formation of toxic metabolites.
Therapeutic use
Anti-infective (topical). Pharmaceutical aid. Therapeutic neurolysis (nerve or ganglion block). Replenishment of fluid and carbohydrate calories.
Pregnancy and lactiation implications
Pregnant women should avoid ethanol intake (teratogenic effects). Ethyl alcohol passes freely into breast milk at a level approximately equivalent to maternal serum level.
Unlabeled use
Antidote for ethylene glycol and for methanol overdose. Treatment of fat occlusion of central venous catheters.
Contraindications
Hypersensitivity to ethyl alcohol or any component of the formulation. Seizure disorder and diabetic coma. Subarachnoid injection of dehydrated alcohol in patients receiving anticoagulants. Pregnancy.
Warnings and precautions
Caution in the following situations: diabetes mellitus (decreases blood sugar), gout, hepatic impairment, shock, and after cranial surgery. Minimize dermal exposure of ethyl alcohol in infants (systemic absorption and toxicity). Use with caution in pregnant women with anticipated postpartum hemorrhage. Should not be administered simultaneously with blood (risk of pseudoagglutination or hemolysis). Not for SubQ administration.