Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Unlabeled Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Italy: Bioarginina.

North America

USA: R-Gene.


Japan: Argi-U, Arginine.

Drug combinations

Arginine: Acetylcysteine; Alanine; Biotin (Vitamin B~7~); Caffeine; Calcium Chloride; Calcium Lactate; Cysteine; Cyanocobalamin (Vitamin B~12~); Dextrose; Folic Acid (Vitamin B~9~); Ginkgo biloba; Ginseng; Glutamic Acid; Glycerol; Glycine; Histidine; Isoleucine; L-Lysine; Leucine; Magnesium Chloride; Methionine; Niacin (Vitamin B~3~); Niacinamide; Ornithine; Phenylalanine; Potassium Chloride; Proline; Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Serine; Sodium Acetate; Sodium Chloride; Sodium Lactate; Sodium Phosphate; Soybean Oil; Threonine; Tryptophan; Valine; Zinc Chloride


Arginine Hydrochloride: C~6~H~14~N~4~O~2~ HCl. Mw: 210.66. L-(+)-Arginine monohydrochloride. CAS-74-79-3 (L-arginine)(1970).

Pharmacologic Category

Diagnostic Agents; Pituitary Function. (ATC-Code: B05XB01).

Mechanism of action

Stimulates pituitary release of growth hormone and prolactin through origins in the hypothalamus.

Therapeutic use

Pituitary function test (growth hormone).

Pregnancy and lactiation implications

Not recommended for use during pregnancy. Use with caution if administered during lactation.

Unlabeled use

Management of severe, uncompensated, metabolic alkalosis after optimizing therapy with sodium and potassium supplements.


Hypersensitivity to arginine or any component of the formulation.

Warnings and precautions

Acute electrolyte disturbances (hyperkalemia, hyponatremia (following overdose), hypophosphatemia, and acidosis) may occur during infusion. Use may lead to life-threatening hyperkalemia in diabetes mellitus, hepatic impairment or in renal impairment. Use with caution in electrolyte imbalance and in children. Avoid use in myocardial infarction.



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