Ascorbic Acid (Vitamin C)

Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Unlabeled Use
  • Pregnancy and Lactation Implications
  • Warnings and Precautions
  • Adverse Reactions
  • Caution and personalized dose adjustment in patients with the following genotypes
  • Other genes that may be involved
  • Substrate of
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Austria: Ascorbin, Cebion Zitrone, Cevitol, Mel-C, Vitamin C; Belgium: Cetamine, Cevi, Redoxon, Upsa, Vitamine C; Bulgaria: Cetebe, Vitamin C; Czech Republic: Acidum Ascorbicum, Additiva Vitamin C, C-Vitamin, Celaskon; Estonia: Vitamin C; Finland: Ascorbin, Cevi, C-Vimin; France: Vitacemil, Vitamine C, Vitascorbol; Germany: Acidum Ascorbicum, Ascorbinsäure, Ascorell, Ascorvit, Cebion, Ceretard, Forum C, Pascorbin, Ursovit, Vagi-C, Vita C, Vitamin C; Greece: Ascorbic Acid, Pascorbin, Vitamin C, Vitorange; Hungary: Pharmavit, Cetebe, Vitamin C; Ireland: Haliborange, Rubex, Vitamin C; Italy: Ac Ascor, Cebion, Cimille, Ctard, Duo C, Dynaphos, Redoxon, Univit, Vici Fte, Vit. C, Vitamin C; Latvia: Cevikap, Vitamin C; Luxembourg: Ascofer, C-Will, Cenol, Cetamine, Cevi, Redoxon, Vitamine C, Vitonic; Malta: Ascorbic Acid; Netherlands: Ascorbinezuur, C-Will, Dayvital, Vitamine C; Poland: Ascorgem, Ascovita, Cebion, Celaskon, Cetebe, Cevikap, Dolovit Vit.C, Juvit, Monovitan, Polovital, Redoxon, Slovit, Top C, Vibovit C, Vicefar, Vicevit, Vitamin C, Witamina C; Portugal: Ácido Ascórbico, Cebiolon, Cebion, Cecon, Cecrisina, C’Nergil, Redoxon, Vitamina C, Vivin; Romania: Cebion, Cetebe, Pascorbin, Redoxon, Vitamin C; Slovakia: Acidum Ascorbicum, Celaskon, C-Vitamin, Vitamin C; Slovenia: Plivit; Spain: Ácido Ascórbico, Cebión, Redoxón; Sweden: C-Vitamin, Ido-C; UK: Ascorbic Acid.

North America

Canada: Activa, Ascorbic Acid, Formula Inf, L’il Critters Gummy Vitamin C, Nutri-Chem Vitamin C, Timed Release Vitamin C, Vitamin C; USA: Acerola, Asco-Caps, Ascocid, C-Gel, C-Gram, C-Time, Cecon, Cemill, Cenolate, Chew-C, Dull-C, Mild-C, One Gram C, Time-C, Vita-C, Vitamin C.

Latin America

Argentina: Cellskinlab Serum, Celuflex C, Cewin, Ctabs-Vit C, C-Vitamin, Gynefix, Plenovit Vit. C, Redoxon, Tanvimil C, Vicenrik, Vitamina C; Brazil: Acerogrip C, Bio-C, Cebion, Cenevit, Cetivit, Cetozone, Cevita, Ceviton, Cewin, Citroplex, Citrovit, Energil C, Fonto-Vit C, Redoxon, Vagi C, Vi-Cê, Vitamicê, Vitamin C, Vitamina C, Vitergyl C; Mexico: AAL, Cevalin, C-Messel, Femiprim, Gomas Garde G, Noratoquín, Oxital, Poly C, Ramy-CE, Redoxón, Sinesmín.


Japan: Actamin C, Ascoltin, Ascorbic Acid, Carashimin C, C-Tuck, Hicee, Mitah-C, VC, Viscorin, Vita C, Vitacimin, Vitacin, Vitamin C.

Drug combinations

Ascorbic Acid and Acetaminophen

Ascorbic Acid and Aspirin

Ascorbic Acid and Ferrous Sulfate

Ascorbic Acid and Ibuprofen

Ascorbic Acid and Piroxicam

Ascorbic Acid and Tocopherol (Vitamin E)

Ascorbic Acid and Zinc

Ascorbic Acid, Acetaminophen, and Aspirin

Ascorbic Acid, Acetaminophen, and Chlorpheniramine

Ascorbic Acid, Acetaminophen, and Diphenhydramine

Ascorbic Acid, Acetaminophen, and Phenylephrine

Ascorbic Acid, Aspirin, and Caffeine

Ascorbic Acid, Aspirin, and Codeine

Ascorbic Acid, Aspirin, and Troxerutin

Ascorbic Acid, Aspirin, Tocopherol (Vitamin E)

Ascorbic Acid, Acetaminophen, Brompheniramine, and Caffeine

Ascorbic Acid, Acetaminophen, Caffeine, and Chlorpheniramine

Ascorbic Acid, Acetaminophen, Dexbrompheniramine, and Pseudoephedrine

Ascorbic Acid, Acetaminophen, Diphenylpyraline, and Ethenzamide

Ascorbic Acid, Acetaminophen, Guaifenesin, and Phenylephrine

Ascorbic Acid, Acetaminophen, Pheniramine, and Phenylephrine

Ascorbic Acid, Acetaminophen, Phenylephrine, and Salicylamide

Ascorbic Acid, Aspirin, Caffeine, and Guaifenesin

Ascorbic Acid, Acetaminophen, Aspartame, Citric Acid, and Phenylephrine

Ascorbic Acid, Acetaminophen, Caffeine, Codeine, Diphenhydramine, and Phenylephrine

Ascorbic Acid, Aluminum Hydroxide, Aspirin, Caffeine, Chlorpheniramine, and Magnesium Carbonate

Other Ascorbic Acid combinations: Adenosine; Biotin (Vitamin B~7~); Calcium; Calcium Carbonate, Calcium Citrate; Calcium Gluconate; Calcium Lactate; Calcium Phosphate, Tribasic; Cyproheptadine; Cholecalciferol (Vitamin D~3~); Cocarboxylase; Cyanocobalamin (Vitamin B~12~); Dexpanthenol; Ergocalciferol (Vitamin D~2~); Ferrous Sulfate; Fluoride; Folic Acid (Vitamin B~9~); Ginkgo biloba; Ginseng; Hawthorn; Magnesium Oxide; Magnesium Phosphate; Manganese; Niacin (Vitamin B~3~); Niacinamide; Pantothenic Acid (Vitamin B~5~); Phenylpropanolamine, Phytomenadione (Vitamin K~1~); Potassium; Pyridoxine (Vitamin B~6~); Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Sodium; Sodium Bicarbonate; Sodium Chloride; Thiamine (Vitamin B~1~); Tocopherol (Vitamin E)


Ascorbic Acid: C~6~H~8~O~6~. Mw: 176.12. L-Ascorbic acid. CAS-50-81-7.

Pharmacologic Category

Vitamins; Vitamin C. (ATC-Code: A11G).

Mechanism of action

Necessary for collagen formation and tissue repair. Involved in some oxidation-reduction reactions as well as other metabolic pathways.

Therapeutic use

Prevention and treatment of scurvy. To acidify urine.

Pregnancy and lactiation implications

Compatible with lactation.

Unlabeled use

Investigational: To decrease the severity of «colds». Dietary supplementation. Possible decreased risk of death by stroke at doses ≥45 mg/day.


Warnings and precautions

Patients with diabetes mellitus as well as those prone to recurrent renal calculi (e.g. dialysis patients) should not take excessive doses for extended periods of time. Some products contain aluminum. Use caution in impaired renal function and in neonates.



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