Biotin (Vitamin B7)
- Atc Codes:A11HA05
- CAS Codes:58-85-5
- PHARMGKB ID:58-85-5
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Caution and personalized dose adjustment in patients with the following genotypes
- Other genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
Europe
Austria: Bio-H-tin, Biogelat, Curatin, Medobiotin; Czech Republic: Biotin, Deacura; Finland: Biotisan; France: Biotine; Germany: Abtei, Bio-H-Tin, Bioro, Biotin, Biotisan, Biovital Biotin, Deacura, Gabunat, Haarna, Natubiotin, Solaguttae, Taxofit; Greece: Biotin, Biotine; Italy: Biodermatin, Diathynil, Nebiotin; Poland: Biotebal; Spain: Medebiotín.
Latin America
Argentina: Aminosam, Biotín, Panabiotín.
Asia
Japan: Biotin.
Drug combinations
Biotin: Arabic Gum; Arginine; Ascorbic Acid (Vitamin C); Barley Flour; Beta-Carotene; Bicarbonate; Calcium; Canola Oil; Carnitine; Carob Gum; Cholecalciferol (Vitamin D~3~); Cholesterol; Chromium; Cinchona Bark Extract; Cistine; Citric Acid; Cocoa Aroma; Coconut Oil; Copper; Corn Oil; Corn Syrup; Cornmeal; Cornstarch; Cyanocobalamin (Vitamin B~12~); Dexpanthenol; Ergocalciferol (Vitamin D~2~); Folic Acid (Vitamin B~9~); Ferrous Fumarate; Gelatina; Ginkgo biloba; Ginseng; Inositol; Iron; Lactose; Linoleic Acid; Linolenic Acid; Magnesium; Malt Extract; Maltodextrin; Manganese; Marigold Extract; Metionine; Molybdenum; Nettle Extract; Niacin (Vitamin B~3~); Niacinamide; Oatmeal; Orange Essence; Palm Oil; Pantothenic Acid (Vitamin B~5~); Paraffin; Phytomenadione (Vitamin K~1~); Pyridoxine (Vitamin B~6~); Quinine; Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Rice Flour; Selenium; Skim Milk; Soluble Lecithin; Soy Lecithin; Soy Protein; Sucrose; Sunflower Oil; Talc; Taurine; Thiamine (Vitamin B~1~); Tocopherol (Vitamin E); Wheat; Zinc
Chemistry
Biotin: C~10~H~16~N~2~O~3~S. Mw: 244.31. (1) 1H-Thieno3,4-dimidazole-4-pentanoic acid, hexahydro-2-oxo-, 3aS-(3aα,4β,6aα)-; (2)(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno [3,4-d] imidazole-4-valeric acid. CAS-58-85-5.
Pharmacologic Category
Vitamins; Vitamin B Complex. (ATC-Code: A11HA05).
Mechanism of action
Biotin is a water-soluble vitamin component of the vitamin B complex. As an essential nutrient, biotin acts as a coenzyme for the body’s carboxylation reactions.
Therapeutic use
Prevention and treatment of biotin deficiency.
Pregnancy and lactiation implications
Use with caution during pregnancy. Compatible with breast-feeding.
Unlabeled use
Contraindications
Biotin should not be used in known allergy or hypersensitivity to any of its ingredients.
Warnings and precautions
Single vitamin deficiency is rare.