Calcium Acetate
- Atc Codes:A12AA12
- CAS Codes:62-54-4
- PHARMGKB ID:62-54-4
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Genes that may be involved
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: Calciumacetat, Phos-Ex, PhosLo, Phosphosorb; Cyprus: Phosphosorb; Czech Republic: Phosphosorb; Denmark: Phos Ex; Estonia: Phos-Ex, Phosphosorb; Finland: Phos-Ex, Phosphosorb; Germany: Calcet, Calciumacetat, Phos-Ex, PhosLo, Phosphosorb, Renacet; Greece: Phosphosorb; Hungary: Phosphosorb; Ireland: Calcium Acetate, Everose, Phosex; Italy: PhosLo; Malta: Phosphosorb; Netherlands: Calciumacetaat, Phos-Ex, PhosLo; Poland: Phosphosorb; Slovakia: Phosphosorb; Slovenia: Phosphosorb; Spain: PhosLo, Royen; Sweden: Phos-Ex, Phosphosorb; UK: Phosex.
North America
Canada: Calcarea Acetica, PhosLo; USA: Eliphos, PhosLo.
Latin America
Argentina: Renacalcio AC, Royen.
Drug combinations
Calcium Acetate and Magnesium Carbonate
Chemistry
Calcium Acetate: C~4~H~6~CaO~4~. Mw: 158.17. Acetic acid, calcium salt. CAS-62-54-4.
Pharmacologic Category
Replacement Preparations. Phosphate-removing Agents. Antidotes. Calcium Salts. (ATC-Code: A12AA12).
Mechanism of action
Calcium moderates nerve and muscle performance via action potential excitation threshold regulation. Calcium acetate combines with dietary phosphate to form insoluble calcium phosphate which is excreted in feces and reduces phosphate absorption.
Therapeutic use
Calcium depletion. Hyperphosphatemia in end-stage renal failure.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Hypersensitivity to any component of the formulation. Hypercalcemia, renal calculi.
Warnings and precautions
Constipation, bloating, and gas are common with calcium supplements. Use with caution in patients who may be at risk of cardiac arrhythmias. Hypercalcemia and hypercalciuria are most likely to occur in hypoparathyroid patients receiving high doses of vitamin D. Use with caution in digitalized patients (hypercalcemia may precipitate cardiac arrhythmias). Calcium administration interferes with absorption of some minerals and drugs (caution).