Calcium Acetate

Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Genes that may be involved
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Austria: Calciumacetat, Phos-Ex, PhosLo, Phosphosorb; Cyprus: Phosphosorb; Czech Republic: Phosphosorb; Denmark: Phos Ex; Estonia: Phos-Ex, Phosphosorb; Finland: Phos-Ex, Phosphosorb; Germany: Calcet, Calciumacetat, Phos-Ex, PhosLo, Phosphosorb, Renacet; Greece: Phosphosorb; Hungary: Phosphosorb; Ireland: Calcium Acetate, Everose, Phosex; Italy: PhosLo; Malta: Phosphosorb; Netherlands: Calciumacetaat, Phos-Ex, PhosLo; Poland: Phosphosorb; Slovakia: Phosphosorb; Slovenia: Phosphosorb; Spain: PhosLo, Royen; Sweden: Phos-Ex, Phosphosorb; UK: Phosex.

North America

Canada: Calcarea Acetica, PhosLo; USA: Eliphos, PhosLo.

Latin America

Argentina: Renacalcio AC, Royen.

Drug combinations

Calcium Acetate and Magnesium Carbonate


Calcium Acetate: C~4~H~6~CaO~4~. Mw: 158.17. Acetic acid, calcium salt. CAS-62-54-4.

Pharmacologic Category

Replacement Preparations. Phosphate-removing Agents. Antidotes. Calcium Salts. (ATC-Code: A12AA12).

Mechanism of action

Calcium moderates nerve and muscle performance via action potential excitation threshold regulation. Calcium acetate combines with dietary phosphate to form insoluble calcium phosphate which is excreted in feces and reduces phosphate absorption.

Therapeutic use

Calcium depletion. Hyperphosphatemia in end-stage renal failure.

Pregnancy and lactiation implications

Unlabeled use


Hypersensitivity to any component of the formulation. Hypercalcemia, renal calculi.

Warnings and precautions

Constipation, bloating, and gas are common with calcium supplements. Use with caution in patients who may be at risk of cardiac arrhythmias. Hypercalcemia and hypercalciuria are most likely to occur in hypoparathyroid patients receiving high doses of vitamin D. Use with caution in digitalized patients (hypercalcemia may precipitate cardiac arrhythmias). Calcium administration interferes with absorption of some minerals and drugs (caution).



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