Calcium Phosphate, Tribasic
- Atc Codes:A12AA01
- CAS Codes:12167-74-7
- PHARMGKB ID:12167-74-7
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Nutrition/Nutraceutical Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
France: Ostram; Greece: Neocalcit, Osteorel; Poland: Ostram; Spain: Ostram.
North America
Canada: Calc. Phos., Calcium Phosphoricum, Calcarea Phosphorica; USA: Posture.
Latin America
Mexico: Calcigenol Doble.
Drugs Combinations
Calcium Phosphate, Tribasic: Ascorbic Acid (Vitamin C); Calcium Citrate; Cholecalciferol (Vitamin D~3~); Copper; Cyanocobalamin (Vitamin B~12~); Cyproheptadine; Ergocalciferol (Vitamin D~2~); Ferrous Sulfate; Folic Acid (Vitamin B~9~); Ginseng; Iron; Magnesium; Niacin (Vitamin B~3~); Niacinamide; Pyridoxine (Vitamin B~6~); Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Selenium; Sodium Glutamate; Thiamine (Vitamin B~1~); Tocopherol (Vitamin E); Zinc Oxide
Drug combinations
Chemistry
Calcium Phosphate, Tribasic: Ca~5~(OH)(PO~4~)~3~. Mw: 502.31. Hydroxyapatite or Hydroxylapatite. CAS-12167-74-7.
Pharmacologic Category
Replacement Preparations. Phosphate-removing Agents. Antidotes. Calcium Salts. Homeopathic products. (ATC-Code: A12AA01).
Mechanism of action
Calcium moderates nerve and muscle performance via action potential excitation threshold regulation. It helps to prevent or decrease the rate of bone loss. It is necessary for maintaining the functional integrity of nervous, muscular, and skeletal systems and cell-membrane and capillary permeability.
Therapeutic use
Dietary supplement. Calcium deficiency. Adjunctive prevention and treatment of osteoporosis.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Hypersensitivity to calcium formulation. Hypercalcemia, renal calculi, ventricular fibrillation.
Warnings and precautions
Constipation, bloating, and gas are common with calcium supplements. Hypercalcemia and hypercalciuria are most likely to occur in hypoparathyroid patients receiving high doses of vitamin D. Use with caution in history of kidney stones. Use with caution in renal failure to avoid hypercalcemia. Calcium administration interferes with absorption of some minerals and drugs. Calcium absorption is impaired in achlorhydria (common in the elderly). It is recommended to administer vitamin D concomitantly for optimal calcium absorption.