Dihydrotachysterol
- Atc Codes:A11CC02
- CAS Codes:67-96-9
- PHARMGKB ID:67-96-9
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: A.T. 10; Czech Republic: Tachystin; Estonia: Tachystin; Finland: Dygratyl; Germany: A.T. 10, Atiten, Tachystin; Ireland: AT 10; Italy: Atiten; Luxembourg: A.T. 10, Dihydral; Netherlands: Dihydral; Romania: A.T. 10; Slovakia: Tachystin; Sweden: Dygratyl; UK: AT 10.
Drug combinations
Chemistry
Dihydrotachysterol: C~28~H~46~O. Mw: 398.66. (1) 9,10-Secoergosta-5,7,22-trien-3-ol, (3β,5E,7E,10α,22E)-; (2) Dihydrotachysterol. CAS-67-96-9.
Pharmacologic Category
Vitamins; Vitamin D. (ATC-Code: A11CC02).
Mechanism of action
Synthetic analog of vitamin D with faster onset of action. Stimulates calcium and phosphate absorption from the small intestine, promotes secretion of calcium from bone to blood. Promotes renal tubule resorption of phosphate.
Therapeutic use
Treatment of hypocalcemia associated with hypoparathyroidism. Prophylaxis of hypocalcemic tetany following thyroid surgery.
Pregnancy and lactiation implications
Enters breast milk and is compatible with lactation.
Unlabeled use
Contraindications
Hypersensitivity to dihydrotachysterol or any component of the formulation. Hypercalcemia. Pregnancy.
Warnings and precautions
Contraindicated in hypercalcemia. Use with caution in coronary artery disease, decreased renal function or renal stones. Use with caution in the elderly.