Ethyl Chloride
- Atc Codes:N01BX01
- CAS Codes:75-00-3
- PHARMGKB ID:75-00-3
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Warnings and Precautions
- Adverse Reactions
- Toxicological Effects
- Drug Interactions
- Dosage
Brand Names
Europe
Greece: Ethyl Chloride; Poland: Aethylum Chloratum; Spain: Cloretilo Chemirosa.
North America
USA: Gebauer’s Ethyl Chloride.
Latin America
Mexico: Traumazol.
Drug combinations
Chemistry
Ethyl Chloride: C~2~H~5~Cl. Mw: 64.51. Chloroethane. CAS-75-00-3.
Pharmacologic Category
Skin and Mucous Membrane Agents; Antipruritics and Local Anesthetics. (ATC-Code: N01BX01).
Mechanism of action
Vapocoolant (skin refrigerant) local anesthetic. Results in tissue hypothermia (-10ºC) when used topically.
Therapeutic use
Used as local anesthetic in minor operative procedures such as incision of carbuncles or furuncles and removal of localized growths. Used to alleviate pain associated with burns and insect stings and that of bruises, contusions, abrasions, swelling, and minor sprains associated with sports injuries. Also used for relief of myofascial and visceral pain syndromes.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Warnings and precautions
Ethyl chloride is highly flammable. Cutaneous sensitization to ethyl chloride may occur rarely. Freezing can occasionally alter pigmentation. The drug should not be applied to broken skin or mucous membranes. Ethyl chloride may be absorbed percutaneously and long-term exposure may result in nephrotoxicity and hepatotoxicity.