Ferrous Fumarate
- Atc Codes:B03AA02#B03AD02
- CAS Codes:141-01-5#110-17-8
- PHARMGKB ID:141-01-5#110-17-8
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Toxicological Effects
- Drug Interactions
- Nutrition/Nutraceutical Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: Ferrobet; Bulgaria: Ferronat; Cyprus: Ferrous Fumarate, Galfer; Czech Republic: Ferronat; France: Fumafer; Germany: Eisenfumarat, Ferrum Hausmann, Rulofer N; Ireland: Fersaday, Galfer; Luxembourg: Ferrum Hausmann; Netherlands: Ferrofumaraat; Romania: Ferronat; Slovakia: Ferronat; UK: Fersaday.
North America
USA: Femiron, Ferretts, Ferro-Sequels, Hemocyte, Ircon, Nephro-Fer.
Latin America
Argentina: Hierro; Mexico: Biofuroso, Croferron, Fernadin, Ferro-Terapina, Ferval, Fumarato Ferroso, Fumavit, Gestaferron.
Asia
Japan: Ferrum.
Drug combinations
Ferrous Fumarate: Ascorbic Acid (Vitamin C); Biotin (Vitamin B~7~); Calcium Carbonate; Calcium Pantothenate; Copper Sulfate; Cyanocobalamin (Vitamin B~12~); Cholecalciferol (Vitamin D~3~); Chromium Nitrate; Ergocalciferol (Vitamin D~2~); Folic Acid (Vitamin B~9~); Magnesium Oxide; Magnesium Phosphate; Manganese; Manganese Sulfate; Methionine; Niacin (Vitamin B~3~); Niacinamide; Potassium Iodide; Pyridoxine (Vitamin B~6~); Retinol (Vitamin A); Riboflavin (Vitamin B~2~); Thiamine (Vitamin B~1~); Tocopherol (Vitamin E); Zinc Sulfate
Chemistry
Ferrous Fumarate: C~4~H~2~FeO~4~. Mw: 169.90. 2-Butenedioic acid, (E)-, iron (2+). CAS-141-01-5; CAS-110-17-8 (fumaric acid).
Pharmacologic Category
Antianemia Drugs; Iron Preparations. Iron Salt. (ATC-Code: B03AA02; B03AD02).
Mechanism of action
Replaces iron found in hemoglobin, myoglobin, and enzymes. Allows transportation of oxygen via hemoglobin.
Therapeutic use
Prevention and treatment of iron-deficiency anemia.
Pregnancy and lactiation implications
Except in severe cases of maternal anemia, the fetus achieves normal iron stores regardless of maternal concentrations. Amount of iron in breast milk generally not influenced by maternal iron status.
Unlabeled use
Contraindications
Hypersensitivity to iron salts or any component of the formulation. Hemochromatosis, hemolytic anemia.
Warnings and precautions
Severe iron toxicity may occur in overdose, particularly when ingested by children. Avoid in peptic ulcer, enteritis, or ulcerative colitis, in patients receiving frequent blood transfusions, or in premature infants until vitamin E stores are replenished.