Anterograde amnesia is possible. May cause CNS depression. Associated with hypersensitivity reactions including anaphylaxis and angioedema. Paradoxical reactions (hyperactive or aggressive behavior), reported with benzodiazepines (particularly in adolescent/pediatric or psychiatric patients). Increased risk for hazardous sleep-related activities exists. Use caution in depression, particularly if suicidal risk may be present. Potential for drug dependency exists (use with caution in history of drug abuse or acute alcoholism). Use with caution in hepatic impairment, impaired gag reflux, renal impairment, or respiratory disease. Effects with other sedative drugs or ethanol may be potentiated. Use with caution in debilitated patients, the elderly, or patients at risk of falls. Abrupt discontinuance may result in withdrawal symptoms. May cause fetal harm if administered during pregnancy. Use with caution in compromised pulmonary function. Potential increased sensitivity (increased risk of oversedation, dizziness, confusion, and/or ataxia) in geriatric patients.