May cause CNS effects (drowsiness and/or blurred vision). Diarrhea may be a sign of incomplete intestinal obstruction (extreme caution). Heat prostration might occur in presence of fever, exposure to high environmental temperatures, and/or exercise. Use with caution in decreased pigmentation (skin and iris coloration, dark vs light). Use with caution in coronary artery disease, tachyarrhythmias, heart failure, or hypertension. Use of anticholinergics in gastric ulcer treatment may cause delay in gastric emptying due to antral statis. Use with caution in hepatic impairment, hiatal hernia with reflux, hyperthyroidism, autonomic neuropathy, prostatic hyperplasia, renal impairment, ulcerative colitis (may precipitate/aggravate toxic megacolon), and in the elderly (increased risk for anticholinergic effects, confusion, and hallucinations). Infants, patients with Down’s syndrome, and children with spastic paralysis or brain damage may be hypersensitive to antimuscarine effects. Not recommended for use in children <12 years of age for management of peptic ulcer or <16 years for preanesthetic use. Injection contains benzyl alcohol, associated with «gasping syndrome» in neonates. Potential risk of curariform neuromuscular blockade resulting in muscle weakness or paralysis with overdosage (avoid overdosage). Caution in esophageal reflux and hiatal hernia. Extreme caution in partial obstructive uropathy. Caution in autonomic neuropathy. Caution in hyperthyroidism.