Iohexol

Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Drug Interactions
  • Dosage

Brand Names

Europe

Austria: Accupaque, Omnipaque; Belgium: Omnipaque; Bulgaria: Omnipaque; Cyprus: Omnipaque; Czech Republic: Omnipaque; Denmark: Omnipaque; Estonia: Omnipaque; Finland: Omnipaque; France: Omnipaque; Germany: Accupaque, Iohexagita, Iohexol, Omnipaque; Greece: Accupaque, Omnipaque; Hungary: Omnipaque; Ireland: Omnipaque; Italy: Omnipaque; Latvia: Omnipaque; Lithuania: Omnipaque; Luxembourg: Omnipaque; Malta: Omnipaque; Netherlands: Omnipaque; Poland: Omnipaque; Romania: Omnipaque; Slovakia: Omnipaque; Spain: Iohexol, Omnipaque, Omnitrast; Sweden: Omnipaque.

North America

Canada: Omnipaque; USA: Omnipaque.

Asia

Japan: Iohexol, Iopaque, Iosol, Ioverin, Moiopaque, Omnipaque.

Drug combinations

Chemistry

Iohexol: C~19~H~26~I~3~N~3~O~9~. Mw: 821.14. (1) 1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N,N’-bis(2,3-dihydroxypropyl)-2,4,6-triiodo; (2) N,N’-Bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide. CAS-66108-95-0 (1980).

Pharmacologic Category

Diagnostic Agents; Imaging Agents; Iodinated Contrast Media. Radiological/Contrast Media (Nonionic, Low Osmolality). (ATC-Code: V08AB02).

Mechanism of action

Therapeutic use

Myelography. Contrast enhancement for computerized tomography. Angiocardiography, aortography, digital subtraction angiography, peripheral arteriography, excretory urography. Contrast enhancement for computed tomographic imaging (intravascular). Arthrography, GI tract examination, hysterosalpingography, pancreatography, cholangiopancreatography, herniography, cystourethrography, enhanced computed tomography of abdomen (oral/body cavity).

Pregnancy and lactiation implications

Fetal harm not observed in animal studies. In general, iodinated contrast media agents are avoided during pregnancy unless essential for diagnosis. Not recommended in nursing women.

Unlabeled use

Contraindications

Hypersensitivity to iohexol or any component of the formulation.

Warnings and precautions

Information

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