Iopamidol
- Atc Codes:V08AB04
- CAS Codes:60166-93-0
- PHARMGKB ID:60166-93-0
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Dosage
Brand Names
Europe
Austria: Gastromiro, Jopamiro, Scanlux; Bulgaria: Iopamiro, Scanlux; Czech Republic: Scanlux; Estonia: Gastromiro, Iopamigita, Iopamiro; Finland: Iopamigita; France: Iopamiron; Germany: Cetegnost, Iopamidol, Iopamigita, Iopamiro, Iopathek, Scanlux, Solutrast, Unilux; Greece: Iopamiro, Radoso, Scanlux; Hungary: Iopamiro, Scanlux; Ireland: Gastromiro, Niopam; Italy: Gastromiro, Iopamidolo, Iopamiro, Iopasen, Scanlux; Latvia: Iopamigita; Lithuania: Iopamiro; Netherlands: Gastromiro, Iopamidol, Iopamiro, Scanlux; Romania: Iopamigita, Iopamiro, Scanlux; Slovakia: Scanlux; Slovenia: Gastromiro, Iopamiro; Spain: Iopamidol, Iopamiro; UK: Gastromiro, Niopam.
North America
Canada: Isovue; USA: Iopamidol, Isovue.
Latin America
Argentina: Iopamiron, Opacrile; Brazil: Iopamiron.
Asia
Japan: Bystage, Hisidol, Iopamiron, Moiopamin, Ovaniron, Oypalomin.
Drug combinations
Chemistry
Iopamidol: C~17~H~22~I~3~N~3~O~8~. Mw: 777.09. (1) 1,3-Benzenedicarboxamide, N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-, (S)-; (2)(S)-N,N’-bis[2-Hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-5-lactamidoisophthalamide. CAS-60166-93-0 (1979).
Pharmacologic Category
Diagnostic Agents; Imaging Agents; Iodinated Contrast Media. Radiological/Contrast Media (Nonionic, Low Osmolality). (ATC-Code: V08AB04).
Mechanism of action
Therapeutic use
Neuroradiology, contrast enhancement of computed tomographic cisternography and ventriculography. Thoraco-lumbar myelography. Angiography, excretory urography, contrast enhancement of computed tomographic imaging, valuation of certain malignancies, image enhancement of non-neoplastic lesions.
Pregnancy and lactiation implications
Fetal harm not observed in animal studies. In general, iodinated contrast media agents are avoided during pregnancy unless essential for diagnosis. Excretion in breast milk unknown (use caution).
Unlabeled use
Contraindications
Hypersensitivity to iopamidol or any component of the formulation.
Drug interactions
Contrast media (non-ionic) may enhance potential for allergic or hypersensitivity reactions to aldesleukin. Iodinated contrast agents may enhance adverse/toxic effect of metformin. Renal dysfunction which may be caused by iodinated contrast agents may lead to metformin-associated lactic acidosis.