Iothalamate Meglumine
- Atc Codes:V09CX03
- CAS Codes:13087-53-1#2276-90-6#6284-40-8
- PHARMGKB ID:13087-53-1#2276-90-6#6284-40-8
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Drug Interactions
- Dosage
Brand Names
Europe
Germany: Conray; Ireland: Conray.
North America
Canada: Conray, Cysto-Conray; USA: Conray.
Drug combinations
Chemistry
Iothalamate Meglumine: C~11~H~9~I~3~N~2~O~4~ C~7~H~17~NO~5~. Mw: 809.13. (1) Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:1); (2) 1-Deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6-triiodo-N-methylisophthalamate. CAS-13087-53-1; CAS-2276-90-6 (iothalamic acid); CAS-6284-40-8 (meglumine).
Pharmacologic Category
Diagnostic Agents; Imaging Agents; Iodinated Contrast Media. Radiological/Contrast Media (Ionic, High Osmolality). Sodium (^125^I)iothalamate. (ATC-Code: V09CX03).
Mechanism of action
Therapeutic use
Arthrography, cerebral angiography, cranial computerized angiotomography, digital subtraction angiography, direct cholangiography, endoscopic retrograde cholangiopancreatography, excretory urography, peripheral arteriography, urography, venography. Contrast enhancement of computed tomographic images (solution for injection). Retrograde cystography and cystourethrography (solution for instillation).
Pregnancy and lactiation implications
In general, iodinated contrast media agents are avoided during pregnancy unless essential for diagnosis. Enters breast milk (use caution).
Unlabeled use
Contraindications
Hypersensitivity to any component of the formulation. Intrathecal administration. Avoid intravascular use of solution for instillation.