Iron Sucrose
- Atc Codes:B03AC02
- CAS Codes:8047-67-4
- PHARMGKB ID:8047-67-4
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: FerMed, Ferrovin, Venofer; Belgium: Venofer; Bulgaria: Venofer; Cyprus: Ferrologic, Venofer; Czech Republic: Ferrologic, Maltofer, Venofer; Denmark: Venofer; Estonia: Ferrologic, Venofer; Finland: Venofer, Venotrix; France: Fer, Venofer; Germany: FerMed, Ferrologic, Nefrofer, Venofer; Greece: Dextrifres S, Faremio, Intrafer-Vianex, Reoxyl; Hungary: Venofer; Ireland: Ferrologic, Venofer; Italy: Ferrum OS, Venofer; Latvia: Venofer; Lithuania: Ferrologic, Venofer; Luxembourg: Venofer; Netherlands: Ferrologic, Ijzerhydroxide Sacharose Complex, Venofer; Poland: Ferrologic, Venofer; Portugal: Óxido Férrico Sacarosado, Referen, Venofer; Romania: Venofer; Slovakia: Ferion, Ferrologic, Venofer; Slovenia: Venofer; Spain: Hierro Sacarosa, Venofer; Sweden: Ferrologic, Venofer; UK: Venofer.
North America
Canada: Venofer; USA: Venofer.
Latin America
Argentina: Energavit.
Drug combinations
Chemistry
Iron Sucrose: Iron saccharate. CAS-8047-67-4 (1998).
Pharmacologic Category
Antianemia Drugs; Iron Preparations. Iron Salt. (ATC-Code: B03AC02).
Mechanism of action
Dissociated by reticuloendothelial system into iron and sucrose. Released iron increases serum iron concentrations and is incorporated into hemoglobin.
Therapeutic use
Treatment of iron-deficiency anemia in chronic renal failure, including non-dialysis-dependent patients (with or without erythropoietin therapy) and dialysis-dependent patients receiving erythropoietin therapy.
Pregnancy and lactiation implications
Teratogenic effects not observed in animal studies. Iron sucrose might be effective for treatment of iron-deficiency anemia in pregnancy. Except in severe cases of maternal anemia, fetus achieves normal iron stores regardless of maternal concentrations. Iron is normally found in breast milk. Use caution in nursing women.
Unlabeled use
Contraindications
Hypersensitivity to iron sucrose or any component of the formulation. Evidence of iron overload. Anemia not caused by iron deficiency.
Warnings and precautions
Hypersensitivity reactions reported (potentially fatal). Possible hypotension associated with I.V. administration. Not FDA-approved for use in children. Withhold iron in presence of tissue iron overload.