Magnesium Citrate
- Atc Codes:A06AD19#A12CC04#B05CB03
- CAS Codes:3344-18-1
- PHARMGKB ID:3344-18-1
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Toxicological Effects
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
North America
Canada: Citro-Mag; USA: Citroma.
Asia
Japan: Macorol, Magcorol, Tectlol.
Drug combinations
Magnesium Citrate: Calcium Citrate
Chemistry
Magnesium Citrate: C~12~H~10~Mg~3~O~14~. Mw: 451.11. 1,2,3-Propanetricarboxylic acid, hydroxy-, magnesium salt (2:3). CAS-3344-18-1.
Pharmacologic Category
Cathartics and Laxatives; Saline Laxatives. Replacement Preparations; Electrolyte Solutions. Nutritional Supplements. Magnesium Salt. (ATC-Code: A06AD19; A12CC04; B05CB03).
Mechanism of action
Promotes bowel evacuation by causing osmotic retention of fluid which distends colon with increased peristaltic activity.
Therapeutic use
Evacuation of bowel prior to certain surgical and diagnostic procedures or overdose situations.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Renal failure. Appendicitis. Abdominal pain. Intestinal impaction, obstruction or perforation. Diabetes mellitus. Complications in gastrointestinal tract. Colostomy or ileostomy. Ulcerative colitis or diverticulitis.
Warnings and precautions
For occasional use only (serious side-effects might occur with prolonged use). Use with extreme caution in myasthenia gravis or other neuromuscular disease. Use with caution in renal impairment (accumulation might lead to magnesium intoxication).