Magnesium Oxide
- Atc Codes:A02AA02#A06AD02#A12CC10
- CAS Codes:1309-48-4
- PHARMGKB ID:1309-48-4
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: Magnonorm; Denmark: Salilax; Germany: Biolectra Magnesium, Magium, Magneherm, Magnetrans Extra, Magno Sanol; Netherlands: Magnesiumoxide; Poland: Magium; Sweden: Salilax.
North America
USA: Mag-Caps, MagGel, Mag-Ox, Uro-Mag.
Asia
Japan: Heavy Magnesium Oxide, Ju-Kama, Kaimax, Light Kama, Maglax, Magmitt.
Drug combinations
Magnesium Oxide and Aspirin
Magnesium Oxide, Aluminum Glycinate, Diazepam, Dicyclomine, Lidocaine, and Simethicone
Other Magnesium Oxide combinations: Aluminium Hydroxide; Aluminium Oxide; Ascorbic Acid (Vitamin C), Belladonna; Benzocaine; Calcium Carbonate; Cysteine; Citric Acid; Dihydroxyaluminum; Ferrous Fumarate; Folic Acid (Vitamin B~9~); Ginseng; Niacin (Vitamin B~3~); Niacinamide; Pyridoxine (Vitamin B~6~); Riboflavin (Vitamin B~2~); Sodium Picosulfate; Tocopherol (Vitamin E)
Chemistry
Magnesium Oxide: MgO. Mw: 40.30. CAS-1309-48-4.
Pharmacologic Category
Antiacids. Replacement Preparations; Electrolyte Solutions. Oral Electrolyte Supplement. Nutritional Supplements. Magnesium Salt. (ATC-Code: A02AA02; A06AD02; A12CC10).
Mechanism of action
Cofactor in protein synthesis and carbohydrate metabolism. Important actions on lipoprotein lipase in reducing serum cholesterol and on sodium/potassium ATPase in promoting polarization (e.g. neuromuscular functioning).
Therapeutic use
Electrolyte replacement.
Pregnancy and lactiation implications
Crosses placenta and is found in breast milk.
Unlabeled use
Contraindications
Hypersensitivity to any component of the formulation.
Warnings and precautions
For occasional use only (serious side-effects might occur with prolonged use). Use with extreme caution in myasthenia gravis or other neuromuscular disease. Use with caution in renal impairment, renal function, hepatitis, or Addison’s disease (accumulation of magnesium might lead to magnesium intoxication).