Magnesium Salicylate
- Atc Codes:N02BA
- CAS Codes:18917-95-8#18917-89-0
- PHARMGKB ID:18917-95-8#18917-89-0
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Drug Interactions
- Nutrition/Nutraceutical Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
Europe
Poland: Salimag.
North America
USA: Doan’s Extra Strength, Keygesic, Momentum Magnesium, Novasal.
Drug combinations
Chemistry
Magnesium Salicylate: C~14~H~10~MgO~6~ 4H~2~O. Mw: 370.59. (1) Magnesium, bis(2-hydroxybenzoato-O^1^,O^2^)-, tetrahydrate; (2) Magnesium salicylate (1:2), tetrahydrate. CAS-18917-95-8; CAS-18917-89-0 (anhydrous).
Pharmacologic Category
Nonsteroidal Anti-inflammatory Agents; Salicylate Salts. (ATC-Code: N02BA).
Mechanism of action
Therapeutic use
Mild-to-moderate pain, fever, various inflammatory conditions. Pain and inflammation of rheumatoid arthritis and osteoarthritis.
Pregnancy and lactiation implications
Specific reproduction studies not conducted. Salicylates excreted into human milk. Breast-feeding not recommended.
Unlabeled use
Contraindications
Hypersensitivity to magnesium salicylate, salicylates, other NSAIDs, or any component of the formulation. Advanced chronic renal dysfunction. With uricosuric agents. History of chronic salicylate use, carditis, chronic liver dysfunction (≥65 years of age).
Warnings and precautions
Patients with sensitivity to tartrazine dyes, nasal polyps, and asthma may have increased risk of salicylate sensitivity. Tinnitus or impaired hearing possible. Use with caution in bleeding disorders. Heavy ethanol use (>3 drinks/day) can increase bleeding risks. Use with caution in dehydration. Use with caution in erosive gastritis or peptic ulcer. Use with caution in hepatic or renal impairment (avoid use in severe impairment). Use high doses with caution in hypoprothrombinemia and/or vitamin K deficiency. Children and teenagers who have or are recovering from chickenpox or flu-like symptoms should not use this product. Changes in behavior (along with nausea and vomiting) might be early sign of Reye’s syndrome. Use with caution prior to surgery (to reduce risk of excessive bleeding).