Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Caution and personalized dose adjustment in patients with the following genotypes
  • Other genes that may be involved
  • Substrate of
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names


Austria: Mepinaest, Scandicaine; Belgium: Scandicaine; Bulgaria: Mepivastesin; Cyprus: Scandonest Plain; Czech Republic: Mepivastesin; Denmark: Carbocain, Scandonest; Estonia: Scandonest Plain; France: Carbocaine, Mepivacaine; Germany: Meaverin, Mecain, Mepicaton, Mepihexal, Mepivacain, Mepivastesin, Scandicain; Greece: Mepivakate, Mepivastesin, Scandonest; Hungary: Scandonest; Ireland: Scandonest; Italy: Carbocaina, Mepi Mynol, Mepibil, Mepicain, Mepiforan, Mepisolver, Mepivac, Mepivamol, Mepivirgi, Pericaina, Scandonest; Luxembourg: Scandicaine; Malta: Scandinibsa, Scandonest; Netherlands: Mepivacaïne, Scandonest; Poland: Carbocaine, Mepidont, Mepivastesin, Scandonest; Portugal: Isogaíne, Mepivacaína, Scandinibsa, Scandonest; Romania: Mepivastesin, Scandonest; Slovakia: Mepivastesin, Scandonest; Slovenia: Scandonest; Spain: Isogaine, Mepivacaína, Scandinibsa; Sweden: Carbocain, Scandonest; UK: Scandonest.

North America

Canada: Carbocaine, Isocaine, Mepivicaine, Polocaine, Scandonest Plain; USA: Carbocaine, Isocaine, Mepivacaine, Polocaine, Scandonest Plain.

Latin America

Argentina: Mepigobbi.


Japan: Carbocain, Scandonest.

Drug combinations

Mepivacaine and Epinephrine

Mepivacaine and Niacinamide

Mepivacaine and Polyestradiol

Mepivacaine, Niacinamide, and Polyestradiol


Mepivacaine Hydrochloride: C~15~H~22~N~2~O HCl. Mw: 282.81. (1) 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride, (±)-; (2)(±)-1-Methyl-2′,6′-pipecoloxylidide monohydrochloride. CAS-1722-62-9; CAS-96-88-8 (mepivacaine).

Pharmacologic Category

Local Anesthetics. (ATC-Code: N01BB03).

Mechanism of action

Acts by preventing generation and conduction of nerve impulses.

Therapeutic use

Local or regional analgesia. Anesthesia by local infiltration, peripheral and central neural techniques including epidural and caudal blocks. Not for use in spinal anesthesia. Local anesthesia by nerve block, infiltration in dental procedures.

Pregnancy and lactiation implications

Animal reproduction studies not conducted. Has been used in obstetrical analgesia. Use caution during lactation (excretion in breast milk unknown).

Unlabeled use


Hypersensitivity to mepivacaine, other amide-type local anesthetics, or any component of the formulation.

Warnings and precautions

Anxiety, blurred vision, dizziness, restlessness, tremor, tinnitus, depression, or drowsiness might be early warning signs of CNS toxicity with local anesthetic injection. Local anesthetics associated with rare occurrences of sudden respiratory arrest. Convulsions due to systemic toxicity leading to cardiac arrest reported, presumably following unintentional intravascular injection. Use with caution in cardiovascular disease, hyperthyroidism, hepatic or renal impairment, acutely ill patients, debilitated patients, and in the elderly. Intravascular injections should be avoided.



Legal Notice
Privacy Policy
Cookie Policy


Phone: +34-981-780505
Location: Sta Marta de, C. P. Babío, S/N, 15165 Bergondo, A Coruña

Copyright © 2023 WAGEM

Add to cart