Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Inhibits
  • Drug Interactions
  • Nutrition/Nutraceutical Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names


France: Lumirelax; Germany: Methocarbamol, Ortoton; Poland: Methocarbamol; Spain: Robaxin; UK: Robaxin.

North America

Canada: Methocarbamol, Robaxin; USA: Methocarbamol, Robaxin.

Latin America

Mexico: Rexivin.


Japan: Robaxin.

Drug combinations

Methocarbamol and Acetaminophen

Methocarbamol and Aspirin


Methocarbamol: C~11~H~15~NO~5~. Mw: 241.24. (1) 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-carbamate, (±)-; (2)(±)-3-(o-Methoxyphenoxy)-1,2-propanediol 1-carbamate. CAS-532-03-6.

Pharmacologic Category

Centrally Acting Skeletal Muscle Relaxants. (ATC-Code: M03BA03).

Mechanism of action

Causes skeletal muscle relaxation by general CNS depression.

Therapeutic use

Treatment of muscle spasm associated with acute painful musculoskeletal conditions. Supportive therapy in tetanus. Treatment of muscle spasm associated with acute temporomandibular joint pain.

Pregnancy and lactiation implications

Animal reproduction studies not conducted. Use during pregnancy only if clearly needed. Excretion in breast milk unknown (use caution).

Unlabeled use


Hypersensitivity to methocarbamol or any component of the formulation. Renal impairment (injection formulation).

Warnings and precautions

Might cause CNS depression. Use with caution in hepatic or renal impairment. Use injection with caution in history of seizure disorder. Effects might be potentiated when used with other sedative drugs or ethanol. Solution is hypertonic (avoid extravasation). Vial stopper contains latex.



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