Might alter cardiac conduction. Phenothiazines might cause anticholinergic effects (constipation, xerostomia, blurred vision, urinary retention) and should be used with caution in decreased GI motility, urinary retention, BPH, xerostomia, or visual problems. Might cause CNS depression. Might cause extrapyramidal symptoms and/or tardive dyskinesia. Might be associated with neuroleptic malignant syndrome. Might cause orthostatic hypotension (use with caution in cardiovascular disease or cerebrovascular disease). Hypotension might occur (particularly when parenteral form is used or in high dosages). Might alter temperature regulation. Use with caution in bone marrow suppression, in severe cardiac disease, in hemodynamically unstable patients, in severe hepatic impairment, in Parkinson’s disease, in breast cancer or other prolactin-dependent tumors (might elevate prolactin levels), in severe renal impairment, in respiratory disease, and in predisposition to seizures. Effects might be potentiated when used with other sedative drugs or ethanol.