Morrhuate Sodium

Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names

North America

USA: Scleromate.

Drug combinations

Chemistry

Morrhuate Sodium: CAS-8031-09-2.

Pharmacologic Category

Cardiovascular Drugs; Sclerosing Agents. (ATC-Code: C05BB).

Mechanism of action

Thrombotic action. Thrombus formed by causing inflammation of vein’s intima. Occlusion secondary to fibrous tissue and thrombus results in obliteration of vein.

Therapeutic use

Treatment of small, uncomplicated varicose veins of lower extremities.

Pregnancy and lactiation implications

Animal reproduction studies not performed with morrhuate sodium. Should be used during pregnancy only when potential benefits justify possible risks to fetus.

Unlabeled use

Contraindications

Hypersensitivity to morrhuate sodium or any component of the formulation. Arterial disease, thrombophlebitis.

Warnings and precautions

Anaphylactoid and allergic reactions have occurred. Sloughing and necrosis of tissue may occur following extravasation. Test dose should be given 24 hours before full-dose treatment.

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