Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Substrate of
  • Drug Interactions
  • Dosage
  • Special Considerations

Brand Names


Austria: Dr. Cabena-Nasentropfen, Nasiben, Nasivin, Wick SinexAloe; Belgium: Nesivine, Vicks Sinex; Bulgaria: Afrin; Czech Republic: Nasivin, Oxamet; Denmark: Iliadin; Estonia: Nazol; Finland: Vicks Sinex; France: Aturgyl, Iliadine, Oxymetazoline, Pernazene; Germany: Nasivin, Oxymetazolin, Vistoxyn, Wick Sinex; Greece: Ezixin, Iliadin, Narol, Ronal, Vicks Vapospray; Hungary: Afrin, Nasivin, Nasopax, Resoxym; Ireland: Iliadin, Oxylin, Vicks Sinex; Italy: Equimet, Narielle, Ossimetazolina, Oxilin, Rino Calyptol, Vicks Sinex; Luxembourg: Nasivin, Vicks Sinex; Netherlands: Nasivin, Oxylin, Vicks Sinex; Poland: Acatar, Afrin, Nasivin, Nosox, Oxalin, Resoxym; Portugal: Alerjon, Bisolspray Nebulicina, Nasarox, Nasex, Oxylin, Rinerge, Sinexsensi, Vicks Vapospray; Romania: Afrin, Nafazin, Nasivin, Oxamet, Rinoxin; Slovakia: Nasivin; Slovenia: Nasivin, Operil; Spain: Alerfrín, Antirrinum, Corilisina, Couldespir, Friresp, Ilvinax, Nasolina, Nebulicina, Oftinal, Otrivín Mentol, Respibien, Respir, Sinexsensi, Utabón, Vicks Spray Nasal; Sweden: Iliadin, Nasin, Nezeril, Vicks Sinex; UK: Boots Nasal Spray, Vicks Sinex.

North America

Canada: Afrin Sinus and Allergy, Claritin Allergic, Dristan, Drixoral Decongestant, Drixoral NO Drip, Long Lasting Nasal, Vicks Sinex, Visine Workplace; USA: Ocuclear, Visine L.R.

Latin America

Argentina: Apracur Nasal, Lidil, Newclar, Panoxi, Rinos VX; Brazil: Aturgyl, Desfrin, Freenal, Nasivin, Oxifrin, Oximetazolina; Mexico: Iliadín, Naztril, Oxylín Liquifilm, Sinex.


Japan: Nasivin, Ocuclear, Operil.

Drug combinations


Oxymetazoline Hydrochloride: C~16~H~24~N~2~O HCl. Mw: 296.84. (1) Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-, monohydrochloride; (2) 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol monohydrochloride. CAS-2315-02-8; CAS-1491-59-4 (oxymetazoline)(1963).

Pharmacologic Category

EENT Preparations; Vasoconstrictors. Adrenergic Agonist Agent. Imidazoline Derivative. (ATC-Code: R01AB07; S01GA04).

Mechanism of action

Stimulates α-adrenergic receptors in arterioles of nasal mucosa to produce vasoconstriction.

Therapeutic use

Adjunctive therapy of middle ear infections, associated with acute or chronic rhinitis, common cold, sinusitis, hay fever, or other allergies. Relief of redness of eye due to minor eye irritations.

Pregnancy and lactiation implications

Unlabeled use


Hypersensitivity to oxymetazoline or any component of the formulation.

Warnings and precautions

Rebound nasal congestion may occur with extended use (>3 days).



Legal Notice
Privacy Policy
Cookie Policy


Phone: +34-981-780505
Email: genomicmedicine@wagem.org
Location: Sta Marta de, C. P. Babío, S/N, 15165 Bergondo, A Coruña

Copyright © 2023 WAGEM

Add to cart