Pancreatin
- Atc Codes:H04
- CAS Codes:8049-47-6
- PHARMGKB ID:8049-47-6
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Austria: Kreon, Pancrin, Panzynorm; Bulgaria: Mezym; Czech Republic: Gastrix, Kreon, Pancreolan, Pangrol, Panzynorm, Panzytrat; Denmark: Kreon; Estonia: Kreon; Finland: Kreon; France: Eurobiol; Germany: Bilipeptal, Enzym-Lefax, Helopan 10.000, Kreon, Lipazym, Mezym, Ozym, Pancrin, Pangrol, Pankreatan, Pankreatin, Pankreon, Panpeptal N, Panpur, Panzynorm, Panzytrat, Unexym; Greece: Panzytrat; Hungary: Dipankrin, Kreon, Mezym, Neo-Panpur, Pangrol, Panzytrat; Ireland: Nutrizym; Latvia: Kreon, Mezym, Pangrol, Panzytrat; Lithuania: Enzystal, Panzytrat; Luxembourg: Hepa-Merz, Panzytrat; Malta: Pancrex V; Netherlands: Panzytrat; Poland: Combizym, Kreon, Lipancrea, Neo-Pancreatinum, Pangrol, Panzytrat; Portugal: Kreon; Romania: Kreon, Mezym, Pangrol; Slovakia: Combizym, Kreon, Pancreolan, Pangrol, Panzynorm, Panzytrat; Slovenia: Kreon; Spain: Digestomen Complex, Kreon; Sweden: Kreon; UK: Nutrizym, Pancrease HL, Pancrex V.
North America
Canada: Azeo-Pangen Pancreatin, Bio-Zyme, Pancreas, Pancreatinum, Pankreas.
Latin America
Argentina: Enzybar, Pancrecura; Brazil: Opti-Free Supraclens, Polyzym; Mexico: Opti-Free.
Asia
Japan: Pancreatin.
Drug combinations
Pancreatin and Simethicone
Other Pancreatin combinations: Aspergillus oryzae enzyme mixture; Bromelain; Cellulase Enzyme; Chymotrypsin; Dehydrocholic Acid; Deoxycholic Acid; Diazepam; Dimethylpolysiloxane; Homatropine; Magnesium; Magnesium Bile Salts, Metoclopramide; Mosapride; Papain; Pepsin; Rutoside; Silymarin; Takadiastasa; Thioctic Acid; Trypsin
Chemistry
Pancreatin: CAS-8049-47-6.
Pharmacologic Category
Gastrointestinal Drugs; Digestants. Enzyme. (ATC-Code: H04).
Mechanism of action
An enzyme supplement, containing combination of lipase, amylase and protease. Enhances digestion of proteins, starch and fat in stomach and intestines.
Therapeutic use
Relief of functional indigestion due to enzyme deficiency or imbalance.
Pregnancy and lactiation implications
Use caution during pregnancy or lactation.
Unlabeled use
Contraindications
Hypersensitivity to pork protein or any component of the formulation. Acute pancreatitis or acute exacerbations of chronic pancreatic disease.
Warnings and precautions
Some products made from pork protein and should not be used if allergic to pork.