Podophyllum Resin

Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names

North America

Canada: Podophyllum, Podophyllinum.

Latin America

Argentina: Cardus Marianus Oligoplex, Cholesterinum Oligoplex, Fel Tauri Oligoplex; Mexico: Podofilia N.2, Vipodo.

Drug combinations


Podophyllum Resin: CAS-8050-60-0.

Pharmacologic Category

Skin and Mucous Membrane Agents, Miscellaneous; Keratolytic Agent. (ATC-Code: D06BB04).

Mechanism of action

Directly affects epithelial cell metabolism by arresting mitosis through binding to protein subunit of spindle microtubules (tubulin).

Therapeutic use

Topical treatment of benign growths including external genital and perianal warts, papillomas, fibroids.

Pregnancy and lactiation implications

Contraindicated in pregnant or breast-feeding women.

Unlabeled use


Not to be used on birthmarks, moles, or warts with hair growth. Cervical, urethral, oral warts. Not to be used with diabetes or poor circulation. Pregnancy.

Warnings and precautions

25% solution should not be applied to or near mucous membranes. Use of large amounts of drug should be avoided. For external use only. Not to be applied to moles, birthmarks, or unusual warts.



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