Podophyllum Resin
- Atc Codes:D06BB04
- CAS Codes:8050-60-0
- PHARMGKB ID:8050-60-0
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
North America
Canada: Podophyllum, Podophyllinum.
Latin America
Argentina: Cardus Marianus Oligoplex, Cholesterinum Oligoplex, Fel Tauri Oligoplex; Mexico: Podofilia N.2, Vipodo.
Drug combinations
Chemistry
Podophyllum Resin: CAS-8050-60-0.
Pharmacologic Category
Skin and Mucous Membrane Agents, Miscellaneous; Keratolytic Agent. (ATC-Code: D06BB04).
Mechanism of action
Directly affects epithelial cell metabolism by arresting mitosis through binding to protein subunit of spindle microtubules (tubulin).
Therapeutic use
Topical treatment of benign growths including external genital and perianal warts, papillomas, fibroids.
Pregnancy and lactiation implications
Contraindicated in pregnant or breast-feeding women.
Unlabeled use
Contraindications
Not to be used on birthmarks, moles, or warts with hair growth. Cervical, urethral, oral warts. Not to be used with diabetes or poor circulation. Pregnancy.
Warnings and precautions
25% solution should not be applied to or near mucous membranes. Use of large amounts of drug should be avoided. For external use only. Not to be applied to moles, birthmarks, or unusual warts.