Povidone-Iodine
- Atc Codes:D08AG02#D09AA09#D11AC06#G01AX11#R02AA15#S01AX18
- CAS Codes:25655-41-8
- PHARMGKB ID:25655-41-8
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
Europe
Austria: Betadona Wund, Betaisodona, Braunol, Braunovidon, Vetisept, Wundesin; Belgium: Braunol, Iodex, Iso-Betadine; Bulgaria: Betadine, Braunol, Braunovidon, Jodasept; Cyprus: Povadyne; Czech Republic: Betadine, Braunol, Braunovidon, Jodisol, Jox; Finland: Betadine, Oculac; France: Betadine, Betaseptic, Povidone Iodee; Germany: Betaisodona, Braunol; Greece: Betadine, Betarem, Bilibidon, Cepton, Drapix, Evapovi-Douche, Evinolut, Igiol, Iodovine, Jodocourir, Leptotest, Libidon, Lombocid, Oxisept, Povidone Iodine, Poviodine, Tinsole, Zanouk; Hungary: Betadine, Gyneiod, Jodoseptic; Ireland: Betadine, Braunoderm, Braunol, Braunosan, Braunovidon, Savlon Dry Antiseptic, Standardised Betadine, Videne; Italy: Betadine; Lithuania: Betadine; Luxembourg: Braunoderm, Braunol, Braunosan, Inadine, Iodex, Iso-Betadine; Netherlands: Betadine, Braunol, Duratears, Protagens; Poland: Betadine, Bolinan, Polodina-R, Polseptol, Povidone Iodine; Portugal: Betadine, Ectodine, Iodolab, Septil; Romania: Betadine, Iodina, Iodosept, Oculotect Fluid; Slovakia: Betadine, Braunol, Braunovidon, Freka-Cid, Jodisol; Slovenia: Betadine, Braunoderm, Braunol; Spain: Betadine, Betatul, Curadona, Liquifresh, Oculotect Sol. oft., Orto-Dermo, Polividona Iodada, Topionic; UK: Betadine.
North America
Canada: FF Sanitizing Hand Cleaner, Scrub, Spray I Dene, Swabplus; USA: Betadine.
Latin America
Argentina: Excelentia Solución Antiséptica, Extraleci, Iodo Povidona, Iodomax, Iopox, Nu-Gel Hidrogel en Placa, Pervinox, Povibac, Povicler, Povi Complex, Povitiol, Tycoytycoy; Brazil: Curativ, Marcodine; Mexico: Isodine, Losine, Yodine.
Asia
Japan: Bongol, Haipopiron, Hisiiode, Homodon, Hypojin, Iodine, Isodine, J-oide, Jisanidine, Microshield, Negmin, Neojodin, Oralon, Polyiodine, Popidon, Popiyodon, Popyiode, Popyral, Popyron, Telnidine.
Drug combinations
Povidone-Iodine and Ethanol
Povidone-Iodine and Isopropyl Alcohol
Povidone-Iodine and Nonoxynol 9
Povidone-Iodine, Glycerol, and Hydroxypropyl Methylcellulose
Other Povidone-Iodine combinations: Fluoride; Sodium Iodide
Chemistry
Povidone-Iodine: (C~6~H~9~NO)~n~ xI. (1) 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine; (2) 1-Vinyl-2-pyrrolidinone polymer, compound with iodine. CAS-25655-41-8.
Pharmacologic Category
Skin and Mucous Membrane Agent; Local Anti-infectives, Miscellaneous. EENT Anti-infectives, Miscellaneous. Ophthalmic Antiseptic. Topical Antiseptic. Vaginal Antiseptic. (ATC-Code: D08AG02; D09AA09; D11AC06; G01AX11; R02AA15; S01AX18).
Mechanism of action
Broad spectrum germicidal agent effective against wide range of bacteria, viruses, fungi, protozoa, and spores.
Therapeutic use
Prevention or treatment of topical infections associated with surgery, burns, minor cuts/scrapes. Relief of minor vaginal irritation.
Pregnancy and lactiation implications
Reproduction studies not conducted. Vaginal products should not be used during pregnancy. Transient hypothyroidism in newborn reported following topical or vaginal use prior to delivery. Enters breast milk (use caution).
Unlabeled use
Contraindications
Hypersensitivity to iodine or any component of the formulation.
Warnings and precautions
Toxicity may occur following application of large or prolonged quantities. Use with caution in burns, in renal impairment, in thyroid disorders, and in children. Should not be applied to deep puncture wounds or serious burns.