Proparacaine
- Atc Codes:N01BA04
- CAS Codes:5875-06-9#499-67-2
- PHARMGKB ID:5875-06-9#499-67-2
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
Brand Names
Europe
Belgium: Alcaine; Bulgaria: Alcaine; Cyprus: Alcaine; Estonia: Alcaine; Germany: Proparakain; Greece: Alcaine; Ireland: Minims Proxymetacaine; Italy: Visuanestetico; Lithuania: Alcaine; Luxembourg: Keracaine; Poland: Alcaine; Slovenia: Alcaine; UK: Minims Proxymetacaine.
North America
Canada: Ak Taine, Alcaine, Diocaine, Ophthetic; USA: Alcaine, Ophthaine, Ophthetic, Proparacaine.
Latin America
Argentina: Anestalcón, Poencaína; Brazil: Anestalcon, Visonest; Mexico: Alcaíne.
Drug combinations
Chemistry
Proparacaine Hydrochloride: C~16~H~26~N~2~O~3~ HCl. Mw: 330.85. (1) Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride; (2) 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride. CAS-5875-06-9; CAS-499-67-2 (proparacaine).
Pharmacologic Category
EENT Preparations; Local Anesthetics. Ophthalmic Local Anesthetic. (ATC-Code: N01BA04).
Mechanism of action
Prevents initiation and transmission of impulse at nerve cell membrane by decreasing ion permeability through stabilizing.
Therapeutic use
Anesthesia for tonometry, gonioscopy. Suture removal from cornea. Removal of corneal foreign body. Cataract extraction, glaucoma surgery. Short operative procedure involving cornea and conjunctiva.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Hypersensitivity to proparacaine or any component of the formulation.
Warnings and precautions
For topical ophthalmic use only. Prolonged use not recommended.