Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Dosage

Brand Names


Belgium: Alcaine; Bulgaria: Alcaine; Cyprus: Alcaine; Estonia: Alcaine; Germany: Proparakain; Greece: Alcaine; Ireland: Minims Proxymetacaine; Italy: Visuanestetico; Lithuania: Alcaine; Luxembourg: Keracaine; Poland: Alcaine; Slovenia: Alcaine; UK: Minims Proxymetacaine.

North America

Canada: Ak Taine, Alcaine, Diocaine, Ophthetic; USA: Alcaine, Ophthaine, Ophthetic, Proparacaine.

Latin America

Argentina: Anestalcón, Poencaína; Brazil: Anestalcon, Visonest; Mexico: Alcaíne.

Drug combinations


Proparacaine Hydrochloride: C~16~H~26~N~2~O~3~ HCl. Mw: 330.85. (1) Benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride; (2) 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride. CAS-5875-06-9; CAS-499-67-2 (proparacaine).

Pharmacologic Category

EENT Preparations; Local Anesthetics. Ophthalmic Local Anesthetic. (ATC-Code: N01BA04).

Mechanism of action

Prevents initiation and transmission of impulse at nerve cell membrane by decreasing ion permeability through stabilizing.

Therapeutic use

Anesthesia for tonometry, gonioscopy. Suture removal from cornea. Removal of corneal foreign body. Cataract extraction, glaucoma surgery. Short operative procedure involving cornea and conjunctiva.

Pregnancy and lactiation implications

Unlabeled use


Hypersensitivity to proparacaine or any component of the formulation.

Warnings and precautions

For topical ophthalmic use only. Prolonged use not recommended.



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