Retinol (Vitamin A)

Table of contents

  • Brand Names
  • Chemistry
  • Drug Combinations
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Caution and personalized dose adjustment in patients with the following genotypes
  • Other genes that may be involved
  • Substrate of
  • Inhibits
  • Induces
  • Drug Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names


Belgium: Vitamuruine; Bulgaria: Oculotect, Vitamin A; Cyprus: Oculotect; Czech Republic: Axerophthol, Vitamin A; Denmark: A-Vitamin; France: A313, Avibon, Vitamine A; Germany: Augen-Kapseln N, Augen-Vit S, Bela-Monovit A, Funktional Vitamin A, Lorett Augenschutz-Kapseln NA, Reti Nit, Solaguttae Augen Vitamin A Kapseln, Solan-M, Taxofit Vitamin A 2500, Vitadral Tropfen, Vitafluid, Vitagel, Vitamin A; Greece: Letrama; Hungary: Vitamin A; Italy: Arovit; Latvia: Vitaminum A; Lithuania: Vitaminas A; Poland: Aksoderm, Capivit A, Dermoretin, Dermosavit, Dermovit A, Oculotect, Vitaminum A; Portugal: A-Vite, Vitaminoftalmina A; Romania: Oculotect, Vitamin A; Slovakia: Axerophthol, Vitamin A; Spain: Auxina A Masiva, Biominol A Hidrosoluble.

North America

USA: Aquasol A.

Latin America

Argentina: Adermicina A Mama, Atomoderma A, A Vitel, Bagovit A, Domsedan, Tanvimil A, Vitamina A; Brazil: Arovit, Lacrigel A, Retinar; Mexico: A Grin, Acon, Dermotin A, Microret, Palmyforte, Retigel-A, Retinol.


Japan: Chocola A.

Drug combinations

Retinol: Actinoquinol; Adenosine; Aloe vera; Ascorbic Acid (Vitamin C); Avena sativa; Benzalkonium; Benzethonium; Benzocaine; Beta-Carotene; Biotin (Vitamin B~7~); Boron; Calcium Carbonate; Calcium Lactate; Calcium Phosphate; Camphor; Chlorhexidine; Cholecalciferol (Vitamin D~3~); Chromium; Chymotrypsin; Cobalt; Cobamamide; Cod liver oil; Copper; Cyanocobalamin (Vitamin B~12~); Cyproheptadine; Deanolorotat; Dexpanthenol; Ergocalciferol (Vitamin D~2~); Ferrous Fumarate; Ferrous Gluconate; Ferrous Sulfate; Fish liver; Fluoride; Folic Acid (Vitamin B~9~); Ginkgo biloba; Ginseng; Glycolic Acid; Hydrocortisone; Hydroxypropyl Methylcellulose; L-Arginine; L-Cysteine; Lidocaine; Magnesium; Manganese; Methionine; Molybdenum; Naphazoline; Neomycin; Niacin (Vitamin B~3~); Niacinamide; Nitrofurazone; Nystatin; Pantothenic Acid (Vitamin B~5~); Papain; Phytonadione (Vitamin K~1~); Piritinol; Pollen; Potassium; Pyridoxine (Vitamin B~6~); Riboflavin (Vitamin B~2~); Rutoside; Saccharomyces cerevisiae; Salicylic Acid; Silicone; Talc; Thiamine (Vitamin B~1~); Thymol; Tocopherol (Vitamin E); Triclosan; Trypsin; Tyrothricin; Ubiquinone; Zinc Oxide; Zinc Sulfate


Retinol: C~20~H~30~O. Mw: 286.23. (1) 3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol. (2) Vitamin A. CAS-68-26-8.

Pharmacologic Category

Vitamins; Vitamin A. (ATC-Code: D10AD02; R01AX02; S01XA02; A11CA01).

Mechanism of action

Needed for bone development, growth, visual adaptation to darkness, testicular and ovarian function, and as cofactor in many biochemical processes.

Therapeutic use

Treatment and prevention of vitamin A deficiency.

Pregnancy and lactiation implications

Excessive use of vitamin A shortly before and during pregnancy could be harmful to babies. Enters breast milk.

Unlabeled use


Hypersensitivity to vitamin A or any component of the formulation. Hypervitaminosis A. Pregnancy (dose exceeding RDA).

Warnings and precautions

In low birth weight infants, polysorbates associated with thrombocytopenia, renal dysfunction, hepatomegaly, cholestasis, ascites, hypotension, and metabolic acidosis (E-Ferol syndrome). Patients receiving >25000 units/day should be closely monitored for toxicity.



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