Saccharomyces boulardii (S. cerevisiae var. boulardii)

Table of contents

  • Brand Names
  • Drug Combinations
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Drug Interactions
  • Dosage
  • Special Considerations

Brand Names


Belgium: Enterol; Bulgaria: Enterol; Cyprus: Bioflor; Czech Republic: Enterol; Denmark: Precosa; Estonia: Enterol; Finland: Precosa; France: Ultra-Levure; Germany: AgioStop Madaus, Boulardii PZ, Hamadin N, Imoflora, Laflor, Medizinische Trockenhefe, Omniflora Akut, Perenterol, Perisal, Perocur, Peromyces, Saccharomyces Aristo, Sükaton Saccharomyces cerevisiae, Testivigor Saccharomyces cerevisiae, Valverde, Vita Hefekapseln gegen Durchfall, Yomogi; Greece: Ultra-Levure; Italy: Codex; Latvia: Enterol; Lithuania: Enterol; Luxembourg: Ultra-Levure; Malta: Bioflor; Poland: Enterol; Portugal: UL-250; Romania: Enterol; Slovakia: Enterol; Spain: Ultra Levura; Sweden: Precosa.

North America

USA: Florastor.

Latin America

Argentina: Floratil; Mexico: Floratil.

Drug combinations

Saccharomyces boulardii: Caffeine; Calcium Lactate; Calcium Gluconate; Ergocalciferol (Vitamin D~2~); Folic Acid (Vitamin B~9~); Ginseng; Niacin (Vitamin B~3~); Niacinamide; Pyridoxine (Vitamin B~6~); Retinol (Vitmain A); Riboflavin (Vitamin B~2~); St. John’s Wort


Pharmacologic Category

Nutritional Supplements. Probiotic. (ATC-Code: A07FA02).

Mechanism of action

A nonpathogenic live yeast probiotic. Acts as temporary flora to help re-establish normal GI microflora. May also modulate immune system by inducing cytokines and suppress pathogenic bacteria growth.

Therapeutic use

Promotes maintenance of normal microflora in GI tract. Bloating, gas, and diarrhea (to decrease incidence of diarrhea associated with antibiotic use).

Pregnancy and lactiation implications

Unlabeled use


Hypersensitivity to Saccharomyces boulardii or any component of the formulation.

Warnings and precautions

Use with caution in allergy to yeast. Avoid use in concurrent systemic antifungals (S. boulardii may be susceptible). Use with caution or avoid use in immunocompromised, debilitated, or critically ill patients (S. boulardii use associated with case reports of fungemia in this population). Some products may contain lactose (caution if lactose intolerance). Significant differences may exist from one preparation of S. boulardii compared to another regarding biologic activity and composition. Probiotics are classified as dietary supplements.



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