Selenium
Table of contents
- Brand Names
- Drug Combinations
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
Europe
Austria: Selekus, Selsun; Belgium: Selsun; Czech Republic: Selenase; Denmark: Selsun; Finland: Selsun, Selukos; France: Granions de Selenium, Oligogranul Selenium, Oligostim Selenium, Plexium Lehning, Selenium, Selsun; Germany: Biochemie Pflüger Nr. 26 Selenium D6, Cefasel, Ellsurex, Heweselen, Naranoselen, Seleject, Selenase, Selenium, Selsun, Selukos, Silenium; Greece: Selenase; Hungary: Selesyn; Ireland: Selsun; Luxembourg: Selenase, Selsun; Malta: Bioselenium; Netherlands: Selenium metallicum; Poland: Cerosel; Portugal: Selenase; Romania: Cefasel; Slovakia: Selenase; Spain: Bioselenium, Caspiselenio; Sweden: Selsun, Selekus.
North America
Canada: Formula 2, Micro Se, Oligostim Selenium, Selenium, Selenium metallicum; USA: Selenium, Selsun.
Latin America
Argentina: Sele200, Selebound; Brazil: Selênio.
Drug combinations
Selenium: Acidum alpha-ketoglutaricum; Acidum arsenicosum; Acidum ascorbicum; Acidum formicicum; Acidum fumaricum; Acidum hydrofluoricum; Acidum lacticum; Acidum phosphoricum; Acidum picrinicum; Acidum silicicum; Acidum sulfuricum; Aconitum napellus; Aesculus hippocastanum; Aluminium oxydatum; Amanita muscaria; Ambra grisea; Ammonium bituminosulfonicum; Anamirta cocculus; Apis mellifica; Arctium spp.; Arctostaphylos uva-ursi; Argentum nitricum; Arnica montana; Artemisia abrotanum; Asparagus officinalis; Atropa bella-donna; Aurum chloratum; Aurum metallicum; Avena sativa; Biotin (Vitamin B~7~); Bryonia spp.; Calcium fluoratum; Calcium Phosphate (Tribasic); Calcium phosphoricum; Camphora; Causticum Hahnemanni; Cerebrum suis; Cerium chloratum; Cinchona pubescens; Cobaltum chloratum; Cobaltum nitricum; Coffeinum; Cola; Conium maculatum; Cor suis; Cortisonum aceticum; Cucurbita pepo; Cuprum aceticum; Cuprum metallicum; Cuprum sulfuricum; Cutis suis; Cyanocobalamin (Vitamin B~12~); Cyanocobalaminum; Chamaelirium luteum; Chininum arsenicosum; Daphne mezereum; Delphinium staphisagria; Dieffenbachia seguine; Diencephalon suis; Digitalis purpurea; Embryo totalis suis; Euspongia officinalis; Ferrum metallicum; Ferrum phosphoricum; Ferrum sesquichloratum solutum; Folic Acid (Vitamin B~9~); Funiculus umbilicalis suis; Galium aparine; Gelsemium sempervirens; Ginkgo biloba; Glandula suprarenalis suis; Graphites; Hepar suis; Hepar sulfuris; Humulus lupulus; Hyoscyamus niger; Hypericum perforatum; Iris versicolor; Kalium arsenicosum; Kalium bichromicum; Kalium carbonicum; Kalium iodatum; Kalium phosphoricum; Kalium picrinicum; Kreosotum; L-Lysine; Lactuca sativa; Ledum palustre; Lien suis; Lycopodium clavatum; Lytta vesicatoria; Magnesium chloratum; Magnesium phosphoricum; Magnesium sulfuricum; Manganum aceticum; Manganum phosphoricum; Manganum sulfuricum; Matricaria recutita; Melilotus officinalis; Mercurius solubilis Hahnemanni; Nasturtium officinale; Natrium carbonicum; Natrium chloratum; Natrium diethyloxalaceticum; Natrium nitricum; Natrium phosphoricum; Natrium sulfuricum; Natrium tetraboracicum; Nicotiana tabacum; Niacin (Vitamin B~3~); Niacinamide; Nicotinamidum; Nitroglycerinum; Nuphar lutea; Ononis spinosa; Panax ginseng; Passiflora incarnata; Petroselinum crispum convar; Phosphorus; Placenta suis; Populus tremula; Pulsatilla pratensis; Riboflavin (Vitamin B~2~); Ruta graveolens; Rutosidum sulfuricum natricum; Selenicereus grandiflorus; Semecarpus anacardium; Sepia officinalis; Serenoa repens; Stannum metallicum; Strychnos ignatii; Strychnos nux-vomica; Sulfur; Sulfur iodatum; Talpa europaea; Terebinthina laricina; Testis suis; Thallium metallicum; Thallium sulfuricum; Thuja occidentalis; Toxicodendron quercifolium; Turnera diffusa; Urtica urens; Vaccinium myrtillus; Valeriana officinalis; Vanadium metallicum; Viscum album; Vitex agnus-castus; Zincum metallicum; Zincum picrinicum; Zincum sulfuricum
Chemistry
Pharmacologic Category
Local Anti-infectives, Miscellaneous. Parenteral Trace Element. Topical Skin Product. Homeopathic product.
Mechanism of action
Part of glutathione peroxidase which protects cell components from oxidative damage due to peroxidases produced in cellular metabolism. May block enzymes involved in growth of epithelial tissue. Antibacterial and mild antifungal activity. Mechanism of action in treatment of dandruff and seborrheic dermatitis not fully determined. Cytostatic (antimitotic) action results in decreased rate of cell turnover in cells with normal or higher than normal turnover rates. Active against Pityrosporum ovale, a yeast-like fungus, part of normal flora of scalp. Local irritant effect.
Therapeutic use
Trace metal supplement. Itching and flaking of the scalp associated with dandruff, to control scalp seborrheic dermatitis. Tinea versicolor.
Pregnancy and lactiation implications
Animal studies not conducted. Avoid use in pregnant women unless potential benefit justifies potential risk to fetus. Excretion in breast milk unknown (use caution).
Unlabeled use
Contraindications
Hypersensitivity to selenium or any component of the formulation.
Warnings and precautions
Avoid topical use in very young children.