Sorbitol
- Atc Codes:A06AD18#A06AG07#B05CX02#V04CC01
- CAS Codes:50-70-4
- PHARMGKB ID:50-70-4
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
Europe
Belgium: Sorbitol; France: Sorbitol; Germany: Sorbitol; Luxembourg: Sorbitol; Portugal: Sorbisteril; Romania: Sorbitol; Slovakia: Infusio Sorbitoli; Sweden: Resulax.
North America
USA: Sorbitol.
Asia
Japan: D-Sorbitol, Uromatic S.
Drug combinations
Sorbitol and Desloratadine
Sorbitol and Docusate Sodium
Sorbitol and Mannitol
Other Sorbitol combinations: Calcium Gluconate; Calcium Lactate; Sodium Lactate; Sodium Citrate; Sodium Laurylsulfate
Chemistry
Sorbitol: C~6~H~14~O~6~. Mw: 182.17. D-Glucitol. CAS-50-70-4.
Pharmacologic Category
Cathartics and Laxatives; Hyperosmotic Laxatives. Irrigating Solutions. Diagnostic Agents; Gallbladder Function. (ATC-Code: A06AD18; A06AG07; B05CX02; V04CC01).
Mechanism of action
A polyalcoholic sugar with osmotic cathartic actions.
Therapeutic use
Genitourinary irrigant in transurethral prostatic resection or other transurethral resection or other transurethral surgical procedures. Diuretic. Humectant. Sweetening agent. Hyperosmotic laxative. To facilitate passage of sodium polystyrene sulfonate through intestinal tract.
Pregnancy and lactiation implications
Excretion in breast milk unknown.
Unlabeled use
Contraindications
Anuria.
Warnings and precautions
Large volumes may result in fluid overload and/or electrolyte changes. Use with caution in severe cardiopulmonary disease, in renal impairment, and in patients unable to metabolize sorbitol.