Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Warnings and Precautions
  • Adverse Reactions
  • Caution and personalized dose adjustment in patients with the following genotypes
  • Dosage
  • Special Considerations

Brand Names

North America

USA: Sclerosol, Talc.

Drug combinations

Talc: Ergocalciferol (Vitamin D~2~); Retinol (Vitamin A); Riboflavin (Vitamin B~2~)


Talc (talk): CAS-14807-96-6.

Pharmacologic Category

Sclerosing Agents.

Mechanism of action

Induces inflammatory reaction which promotes adherence of visceral to parietal pleura, therefore preventing reaccumulation of pleural fluid.

Therapeutic use

Prevention of recurrence of malignant pleural effusion in symptomatic patients.

Pregnancy and lactiation implications

Use only if potential benefit outweighs possible risk to fetus.

Unlabeled use


Warnings and precautions

Acute pneumonitis and acute respiratory distress syndrome (including one death) rarely reported with higher doses (10 g). Should not be used to treat malignancies. Does not have antineoplastic activity. Sclerosis of pleural space may preclude subsequent procedures (e.g. pneumonectomy for transplantation).



Legal Notice
Privacy Policy
Cookie Policy


Phone: +34-981-780505
Email: genomicmedicine@wagem.org
Location: Sta Marta de, C. P. Babío, S/N, 15165 Bergondo, A Coruña

Copyright © 2023 WAGEM

Add to cart