Tetrahydrozoline
- Atc Codes:R01AA06
- CAS Codes:522-48-5#84-22-0
- PHARMGKB ID:522-48-5#84-22-0
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Adverse Reactions
- Drug Interactions
- Dosage
- Special Considerations
Brand Names
Europe
Belgium: Visine; Bulgaria: Sensilux, Visine; Cyprus: Vasopos N, Vispring; Czech Republic: Vasopos N, Visine Classic; Denmark: Tyzine, Visine Visiclear; Estonia: Visine Classic; Finland: Oftan-Starine, Visclear; Germany: Berberil N, Caltheon, Ophtalmin-N, Rhinex Nasenspray mit Tetryzolin, Tetrilin, Tetryzolin, Vasopos N, Visine; Greece: Ursa-Fin, Vispring; Hungary: Spersallerg, Visine Classic; Italy: Demetil, Eyedec, Octilia, Stilla, Vasorinil, Visustrin; Latvia: Visine; Lithuania: Visine Classic; Luxembourg: Berberil; Poland: Berberil, Starazolin, Tetryvil, Visine Clasic, Zalbion; Portugal: Visine; Romania: Vasopos, Visine Classic, Vizoptin; Slovakia: Sensilux, Visine Classic; Slovenia: VisiClear; Spain: Azulina, Vispring.
North America
Canada: Eye Drops, Visine Original; USA: Tyzine.
Latin America
Argentina: Baño Ocular Poen, Chiosan, Irix, Ocudiafan, Piam, Visubril; Mexico: Eye-Mo Rojo, Tetrazol.
Asia
Japan: Narbel.
Drug combinations
Tetrahydrozoline and Antazoline
Tetrahydrozoline and Chlorpheniramine
Tetrahydrozoline and Cromolyn
Tetrahydrozoline and Fluorometholone
Tetrahydrozoline and Pheniramine
Tetrahydrozoline, Dexamethasone, and Gentamicin
Chemistry
Tetrahydrozoline Hydrochloride: C~13~H~16~N~2~ HCl. Mw: 236.74. (1) 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, monohydrochloride; (2) 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline monohydrochloride. CAS-522-48-5; CAS-84-22-0 (tetrahydrozoline).
Pharmacologic Category
EENT Preparations; Vasoconstrictors. Adrenergic Agonist Agent. Imidazoline Derivative. Ophthalmic Agent. (ATC-Code: R01AA06).
Mechanism of action
Stimulates α-adrenergic receptors in arterioles of conjunctiva and nasal mucosa to produce vasoconstriction.
Therapeutic use
Symptomatic relief of nasal congestion and conjunctival congestion.