Tetrahydrozoline

Table of contents

  • Brand Names
  • Drug Combinations
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Adverse Reactions
  • Drug Interactions
  • Dosage
  • Special Considerations

Brand Names

Europe

Belgium: Visine; Bulgaria: Sensilux, Visine; Cyprus: Vasopos N, Vispring; Czech Republic: Vasopos N, Visine Classic; Denmark: Tyzine, Visine Visiclear; Estonia: Visine Classic; Finland: Oftan-Starine, Visclear; Germany: Berberil N, Caltheon, Ophtalmin-N, Rhinex Nasenspray mit Tetryzolin, Tetrilin, Tetryzolin, Vasopos N, Visine; Greece: Ursa-Fin, Vispring; Hungary: Spersallerg, Visine Classic; Italy: Demetil, Eyedec, Octilia, Stilla, Vasorinil, Visustrin; Latvia: Visine; Lithuania: Visine Classic; Luxembourg: Berberil; Poland: Berberil, Starazolin, Tetryvil, Visine Clasic, Zalbion; Portugal: Visine; Romania: Vasopos, Visine Classic, Vizoptin; Slovakia: Sensilux, Visine Classic; Slovenia: VisiClear; Spain: Azulina, Vispring.

North America

Canada: Eye Drops, Visine Original; USA: Tyzine.

Latin America

Argentina: Baño Ocular Poen, Chiosan, Irix, Ocudiafan, Piam, Visubril; Mexico: Eye-Mo Rojo, Tetrazol.

Asia

Japan: Narbel.

Drug combinations

Tetrahydrozoline and Antazoline

Tetrahydrozoline and Chlorpheniramine

Tetrahydrozoline and Cromolyn

Tetrahydrozoline and Fluorometholone

Tetrahydrozoline and Pheniramine

Tetrahydrozoline, Dexamethasone, and Gentamicin

Chemistry

Tetrahydrozoline Hydrochloride: C~13~H~16~N~2~ HCl. Mw: 236.74. (1) 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, monohydrochloride; (2) 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline monohydrochloride. CAS-522-48-5; CAS-84-22-0 (tetrahydrozoline).

Pharmacologic Category

EENT Preparations; Vasoconstrictors. Adrenergic Agonist Agent. Imidazoline Derivative. Ophthalmic Agent. (ATC-Code: R01AA06).

Mechanism of action

Stimulates α-adrenergic receptors in arterioles of conjunctiva and nasal mucosa to produce vasoconstriction.

Therapeutic use

Symptomatic relief of nasal congestion and conjunctival congestion.

Pregnancy and lactiation implications

Unlabeled use

Contraindications

Warnings and precautions

Information

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