Tropicamide
- Atc Codes:S01FA06
- CAS Codes:1508-75-4
- PHARMGKB ID:1508-75-4
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Dosage
- Special Considerations
Brand Names
Europe
Austria: Mydriaticum; Belgium: Mydriacyl, Tropicamide, Tropicol; Bulgaria: Mydrum; Czech Republic: Mydrum, Unitropic; Denmark: Mydriacyl; Estonia: Mydriacyl; Finland: Oftan Tropicamid; France: Mydriaticum; Germany: Mydriaticum, Mydrum, Tropa; Greece: Tropixal; Hungary: Mydrum; Ireland: Mydriacyl, Tropicamide; Italy: Tropimil, Visumidriatic; Latvia: Mydriacyl; Lithuania: Tropicamidum; Luxembourg: Mydriaticum, Tropicol; Malta: Tropicamide; Netherlands: Tropicamide; Poland: Mydriacyl, Tropicabion, Tropicamidum; Portugal: Tropicil Top; Romania: Mydriacyl, Mydrum, Tropicamida, Tropixal; Slovakia: Mydrum, Unitropic; Slovenia: Mydriacyl; Spain: Tropicamida; Sweden: Mydriacyl, Tropikamid; UK: Mydriacyl, Tropicamide.
North America
Canada: Diotrope, Mydriacyl; USA: Mydriacyl, Tropicacyl, Tropicamide.
Latin America
Argentina: Mydril; Brazil: Ciclomidrin, Mydriacyl, Tropinom; Mexico: Myriacil.
Asia
Japan: Mydrin, Sandol.
Drug combinations
Tropicamide and Hydroxyamphetamine
Tropicamide and Phenylephrine
Chemistry
Tropicamide: C~17~H~20~N~2~O~2~. Mw: 284.35. (1) Benzeneacetamide, N-ethyl-α-(hydroxymethyl)-N-(4-pyridinylmethyl)-, (±)-; (2)(±)-N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide. CAS-1508-75-4 (1962).
Pharmacologic Category
EENT Preparation; Mydriatics. (ATC-Code: S01FA06).
Mechanism of action
Prevents sphincter muscle of iris and muscle of ciliary body from responding to cholinergic stimulation.
Therapeutic use
Short-acting mydriatic used in diagnostic procedures, as well as preoperatively and postoperatively. Treatment of some cases of acute iritis, iridocyclitis, and keratitis.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Hypersensitivity to tropicamide or any component of the formulation. Glaucoma.
Warnings and precautions
May cause increase in intraocular pressure. Contact lenses should be removed before using. Use with caution in infants and children (may cause potentially dangerous CNS disturbances).