Trypan Blue
- Atc Codes:S01K
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Dosage
Brand Names
North America
Canada: D.O.R.C. Vision Blue; USA: Membraneblue, VisionBlue.
Drug combinations
Chemistry
Trypan Blue: C~34~H~24~N~6~Na~4~O~14~S~4~. Mw: 960.8. 3,3′-[(3,3′-dimethyl-4,4′-biphenylylene) bis(azo)]bis(5-amino-4-hydroxy-2,7-naphthalenedisulfonic acid) tetra sodium salt.
Pharmacologic Category
Other Miscellaneous Therapeutic Agents. Surgical Aids. Ophthalmic Agent. (ATC-Code: S01K).
Mechanism of action
An acid di-azo group dye which selectively stains connective tissue structures in human eye.
Therapeutic use
Staining of anterior capsule of the lens during cataract surgery.
Pregnancy and lactiation implications
Teratogenic effects, increased fetal mortality, and decreased fetal weight observed following systemic use in animal studies. Excretion in breast milk unknown (use with caution in nursing women).
Unlabeled use
Contraindications
Hypersensitivity to trypan blue or any component of the formulation. Nonhydrated, hydrophilic acrylic intraocular lens insertion (IOL).
Warnings and precautions
Irrigate to remove excess solution following injection. Dye may be absorbed by, and stain, a nonhydrated hydrophilic acrylic IOL.