Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Nutrition/Nutraceutical Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics

Brand Names


Bulgaria: Cavinton, Vicerin, Vinpocetine; Czech Republic: Cavinton, Vicebrol, Vinpocetine; Hungary: Cavinton, Vinpocetin; Lithuania: Cavinton, Vinpocetine; Poland: Cavinton, Recervin, Vicebrol, Vinpocetine, Vinpoton; Portugal: Cavinton, Ultravinca, Vinpocetina, Vipocem; Romania: Cavinton, Vicebrol, Vinpocetin; Slovakia: Cavinton, Vinpocetine; Spain: Vinpocetina.

Drug combinations


Vinpocetine: C~22~H~26~N~2~O~2~. Mw: 350.45. (1) Ebunarmenine-14-carboxylic acid, ethyl ester, (3α, 16α); (2) Ethyl apovincamin-22-oate. CAS-42971-09-5 (1981).

Pharmacologic Category

Anti-Dementia Agents; Vasoactive agents. Vincamine Derivative. Nutritional Supplements. (ATC-Code: N06BX18).

Mechanism of action

Possesses various mechanisms of action: effects on brain circulation and oxygen utilization without changes in systemic circulation, increased tolerance of brain to vascular hypoxia and ischemia, anticonvulsant activity, phosphodiesterase-1 inhibition, and lowering of blood viscosity and inhibition of aggregation of thrombocytes.

Therapeutic use

Treatment of cognitive disorders associated with cerebral vascular pathology.

Pregnancy and lactiation implications

Use should be avoided during pregnancy and lactation.

Unlabeled use


Should not be used in severe, general, cerebral hypertensive crises, or in elderly or senile patients with acute cardio-cerebral or cerebro-cardiac syndrome, postinfarction cardiosclerosis, or marked disorders of heart rhythm.

Warnings and precautions



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