Meningococcal Group C-CRM197 Conjugate Vaccine
- Atc Codes:J07AH
Table of contents
- Brand Names
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
Brand Names
Europe
Austria: Meningitec, Menjugate; Belgium: Meningitec, Menjugate; Cyprus: Meningitec; Czech Republic: Menjugate; France: Meningitec, Menjugatekit; Germany: Meningitec, Menjugate; Greece: Meningitec, Menjugate; Hungary: Meningitec, Menjugate; Ireland: Meningitec, Menjugate Kit; Italy: Meningitec, Menjugate Kit; Luxembourg: Menjugate; Malta: Meningitec; Netherlands: Meningitec, Menjugate; Poland: Meningitec; Portugal: Meningitec, Menjugate Kit; Romania: Menjugate; Spain: Meningitec, Menjugate Kit; Sweden: Meningitec, Menjugate Set; UK: Meningitec, Menjugate Kit.
North America
Canada: Meningitec, Menjugate.
Drug combinations
Chemistry
Pharmacologic Category
Serums, Toxoids, and Vaccines; Vaccines. (ATC-Code: J07AH).
Mechanism of action
Induces immunity against meningococcal disease via formation of bactericidal antibodies directed toward polysaccharide capsular components of Neisseria meningitidis serogroup C.
Therapeutic use
Provides active immunization against invasive meningococcal disease caused by N. meningitidis serogroup C, in children ≥2 months and adults.
Pregnancy and lactiation implications
Animal studies have not demonstrated risks to fetus. Reproductive studies in humans not conducted to date. Excretion in breast milk unknown (use caution).
Unlabeled use
Contraindications
Hypersensitivity to meningococcal group C-CRM197 conjugate vaccine or any component of the formulation.
Warnings and precautions
Anaphylactoid and/or hypersensitivity reactions might occur. May be administered in mild acute illness without fever. Use with caution in history of bleeding disorders (including thrombocytopenia) and/or patients on anticoagulant therapy (bleeding/hematoma may occur from intramuscular administration). Not intended for immunization against diphtheria. Not to be used to treat meningococcal infections or to provide immunity against N. meningitidis serogroups A, B, 29-E, H, I, K, L, W-135, X, Y, or Z. Use with caution in severely immunocompromised patients (e.g. HIV, patients receiving chemo/radiation therapy or other immunosuppressive therapy).