Aminosalicylic Acid

Table of contents

  • Brand Names
  • Chemistry
  • Pharmacologic Category
  • Mechanism of Action
  • Therapeutic Use
  • Unlabeled Use
  • Pregnancy and Lactation Implications
  • Contraindications
  • Warnings and Precautions
  • Adverse Reactions
  • Genes that may be involved
  • Drug Interactions
  • Nutrition/Nutraceutical Interactions
  • Dosage
  • Pharmacokinetics and Pharmacodynamics
  • Special Considerations

Brand Names

North America

USA: Paser.

Drug combinations


Aminosalicylic Acid: C~7~H~7~NO~3~. Mw: 153.14. Benzoic acid, 4-amino-2-hydroxy-. CAS-65-49-6.

Aminosalicylate Sodium: C~7~H~6~NNaO~3~ 2H~2~O. Mw: 211.15. Monosodium 4-aminosalicylate dihydrate. CAS-6018-19-5; CAS-133-10-8 (anhydrous).

Pharmacologic Category

Antituberculosis Agents; Salicylate. (ATC-Code: J04AA01).

Mechanism of action

Competitive antagonism with para-aminobenzoic acid (PABA). Disrupts plate biosynthesis in sensitive organisms.

Therapeutic use

Adjunctive treatment of tuberculosis.

Pregnancy and lactiation implications

Use during pregnancy only if clearly needed. Not recommended during lactation.

Unlabeled use

Crohn’s disease.


Hypersensitivity to aminosalicylic acid or any component of the formulation.

Warnings and precautions

Increased risk of salicylate sensitivity in patients with sensitivity to tartrazine dyes, nasal polyps, or asthma. Use with caution in gastric ulcer, hepatic or renal impairment.



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