Crotamiton
- Atc Codes:D04AX
- CAS Codes:483-63-6
- PHARMGKB ID:483-63-6
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Dosage
Brand Names
Europe
Belgium: Eurax; France: Eurax; Germany: Crotamitex, Eraxil; Ireland: Eurax; Italy: Eurax; Luxembourg: Eurax; Malta: Eurax; Poland: Crotamiton; Portugal: Eurax, Scabicin; Slovenia: Eurax; UK: Eurax.
North America
Canada: Eurax; USA: Crotan, Eurax.
Latin America
Mexico: Acomexol, Eurax.
Asia
Japan: Crotamiton, Eurax.
Drug combinations
Chemistry
Crotamiton: C~13~H~17~NO. Mw: 203.28. 2-Butenamide, N-ethyl-N-(2-methylphenyl)-; (2) N-Ethyl-o-crotonotoluidide. CAS-483-63-6.
Pharmacologic Category
Skin and Mucous Membrane Agents; Anti-infectives; Scabicides and Pediculicides. Antipruritic. (ATC-Code: D04AX).
Mechanism of action
Active against Sarcoptes scabiei (mite which causes scabies), Pediculus humanus var. capitis (head louse), and Pediculus humanus var. corporis (body louse). Mechanisms of action are not known.
Therapeutic use
Scabies (Sarcoptes scabiei). Pruritus.
Pregnancy and lactiation implications
Animal reproduction studies not conducted. Use during pregnancy only if clearly needed. Excretion in breast milk unknown.
Unlabeled use
Contraindications
Hypersensitivity to crotamiton or any component of the formulation. Primary irritation response to topical medications.
Warnings and precautions
For external use only. Should not be applied to acutely inflamed or raw skin.