Iodoquinol
- Atc Codes:G01AC01
- CAS Codes:83-73-8
- PHARMGKB ID:83-73-8
Table of contents
- Brand Names
- Drug Combinations
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
- Special Considerations
Brand Names
North America
Canada: Diodoquin.
Latin America
Mexico: Ameban, Antidifar, Carsuquin, Diodoquin, Diyosul, Entero-Diyod, Quinosul, Versamiv.
Drug combinations
Iodoquinol and Metronidazole
Iodoquinol, Boric Acid, Sodium Propionate, Zinc Oxide, and Zinc Undecylenate
Chemistry
Iodoquinol: C~9~H~5~I~2~NO. Mw: 396.95. (1) 8-Quinolinol, 5,7-diiodo-; (2) 5,7-Diiodo-8-quinolinol. CAS-83-73-8 (1980).
Pharmacologic Category
Antiprotozoals; Amebicides. (ATC-Code: G01AC01).
Mechanism of action
Works in lumen of intestine by unknown mechanism.
Therapeutic use
Treatment of acute and chronic intestinal amebiasis. Asymptomatic cyst passers. Blastocystis hominis infections.
Pregnancy and lactiation implications
Safe use of iodoquinol during pregnancy or lactation not established.
Unlabeled use
Contraindications
Hypersensitivity to iodine or iodoquinol or any component of the formulation. Hepatic damage. Pre-existing optic neuropathy.
Warnings and precautions
Hypersensitivity reactions might occur. Optic neuritis and optic atrophy possible (with prolonged use). Use with caution in thyroid abnormalities.