Levocabastine
- Atc Codes:R01AC02#S01GX02
- CAS Codes:79547-78-7#79516-68-0
- PHARMGKB ID:79547-78-7#79516-68-0
Table of contents
- Brand Names
- Chemistry
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Genes that may be involved
- Drug Interactions
- Dosage
- Pharmacokinetics and Pharmacodynamics
Brand Names
Europe
Austria: Livostin; Belgium: Livostin; Czech Republic: Livostin; Denmark: Livostin; Finland: Livostin; France: Levophta; Germany: Livocab, Livostin; Greece: Livostin; Hungary: Livostin; Italy: Levoreact, Levostab, Livostin; Luxembourg: Livostin; Malta: Livostin; Netherlands: Livocab; Poland: Histimet; Portugal: Livostin; Slovakia: Livostin; Spain: Bilina, Livocab; Sweden: Livocab, Livostin.
North America
Canada: Livostin.
Latin America
Argentina: Histimet; Brazil: Livostin; Mexico: Livostin.
Asia
Japan: Levocabastine, Livostin.
Drug combinations
Chemistry
Levocabastine Hydrochloride: C~26~H~29~FN~2~O~2~ HCl. Mw: 456.98. (1) 4-Piperidinecarboxylic acid, 1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-, monohydrochloride, (-)-[1(cis),3α,4β]-; (2)(-)-trans-1-[cis-4-Cyano-4-(p-fluorophenyl)cyclohexyl]-3-methyl-4-phenylisonipecotic acid monohydrochloride. CAS-79547-78-7; CAS-79516-68-0 (levocabastine)(1985).
Pharmacologic Category
Second Generation Antihistamines. EENT Preparations; Antiallergic Agents; Histamine H~1~ Antagonist. (ATC-Code: R01AC02; S01GX02).
Mechanism of action
Potent, selective histamine H~1~-receptor antagonist for topical ophthalmic use.
Therapeutic use
Treatment of allergic conjunctivitis.
Pregnancy and lactiation implications
Unlabeled use
Contraindications
Hypersensitivity to levocabastine or any component of the product. Use while soft contact lenses are being worn.
Warnings and precautions
Should not be used with soft contact lenses. For topical ophthalmic use only.