Measles Virus Vaccine (Live)
- Atc Codes:J07BD01
Table of contents
- Brand Names
- Drug Combinations
- Pharmacologic Category
- Mechanism of Action
- Therapeutic Use
- Pregnancy and Lactation Implications
- Contraindications
- Warnings and Precautions
- Adverse Reactions
- Caution and personalized dose adjustment in patients with the following genotypes
- Drug Interactions
- Dosage
- Special Considerations
Brand Names
Europe
North America
USA: Attenuvax.
Asia
Japan: Biken, Freeze-dried live attenuated measles vaccine.
Drug combinations
Measles, Mumps, and Rubella Vaccines
Measles, Mumps, Rubella and Varicella Virus Vaccine
Chemistry
Pharmacologic Category
Serums, Toxoids, and Vaccines; Vaccines. Live Viral Vaccine. (ATC-Code: J07BD01).
Mechanism of action
Promotes active immunity to measles virus by inducing specific measles IgG and IgM antibodies.
Therapeutic use
Active immunization against measles (rubeola).
Pregnancy and lactiation implications
Reproduction studies not conducted. Vaccine should not be administered to pregnant women. Infection with natural measles during pregnancy may increase risk of spontaneous abortion, stillbirth, congenital defects and prematurity. Breast-feeding not a contraindication to vaccination.
Unlabeled use
Contraindications
Hypersensitivity to measles vaccine or any component of the formulation. Current febrile illness. Patients receiving immunosuppressive therapy (not including steroid replacement). Primary and acquired immunodeficiency states. Blood dyscrasias, cancers affecting bone marrow or lymphatic systems. Pregnancy.
Warnings and precautions
Anaphylactoid/hypersensitivity reactions (use extreme caution in immediate-type hypersensitivity reactions to eggs). Contact dermatitis to neomycin not a contraindication to vaccine. Use with caution in history of cerebral injury, seizures, or other conditions where stress due to fever should be avoided. Exposure to measles not a contraindication to vaccine. Use with caution in thrombocytopenia and patients who develop thrombocytopenia after first dose (thrombocytopenia may worsen). Recent administration of immune globulins may interfere with immune response. Use contraindicated in severely immunocompromised patients (may have reduced response to vaccination). Products may contain albumin, gelatin or neomycin. Recent administration of blood or blood products may interfere with immune response.